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  • Raw Data Question

    In Raw Data, each SNP lists the base of each position on each chromosome you inherit from each parent.

    ie)rs3131972 1 742584 AG
    A is the base of chromosome received from parent A at that position
    G is the base of chromosome received from parent B at that position

    Now looking at ONLY Chromosome 1 as an example, does anyone know if results are listed according to left letter representing Parent A and right letter as Parent B

    ie)
    rs3131972 1 742584 AG
    rs12562034 1 758311 GG
    rs12124819 1 766409 AG
    rs11240777 1 788822 AG
    rs6681049 1 789870 CC
    rs4970383 1 828418 CC
    rs4475691 1 836671 CC

    Parent A base sequence would be AGAACCC
    Parent B base sequence would be GGGGCCC

    Or is letter representation mixed, each base pair listed could come from either Parent A or Parent B.

  • #2
    Originally posted by prairielad View Post
    Or is letter representation mixed, each base pair listed could come from either Parent A or Parent B.
    This one. they are all mixed up. You have to compare the entire list to a parent, thus phasing it.

    Matt.

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    • #3
      Originally posted by mkdexter View Post
      This one. they are all mixed up. You have to compare the entire list to a parent, thus phasing it.

      Matt.
      That is what I figured when comparing two siblings kits together.

      Is there a way of phasing using siblings results. My Test kits are of siblings (my father and his sister). I plan to test all my fathers siblings, 3 more sisters and 2 brothers.

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      • #4
        Phasing

        RE "Is there a way of phasing using siblings results. My Test kits are of siblings (my father and his sister). I plan to test all my fathers siblings, 3 more sisters and 2 brothers. "

        In general phasing is done using ancestors (Parents/Grandparents/Aunts/Uncles)
        or cousins is you know the side (maternal/paternal)
        Using siblings has many logic problems but can be useful for short segments
        where you are sure there are no crossovers.
        Phasing has great value in reducing the random Identical By State, IBS matches
        that show up at the 12 cM and less lengths
        I have heard that one can deduce a parents DNA from 4 children you will have
        six do maybe you can deduce your grand parents.
        I suspect this will require a lot of manual work an a segment by segment
        chromosome by chromosome bassis

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