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Build 36/37 autosomal and x chromosome

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  • Build 36/37 autosomal and x chromosome

    I'm wanting to upload my x chromosome and autosomal chromosome raw data to GEDmatch. Why am I given the options of

    Build 36 or Build 37 x and autosomal chromosome raw data?

    I'm a male, I have one x chromosome. what's the difference between 36 and 37 and do I need to upload all 4 files to GEDmatch?


    Thanks!

  • #2
    I think I just found the answer, I need to do Build 36 for both x and autosomal. I'm not sure what the 36 and 37 mean though

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    • #3
      Each Build is a versions of human genome reference

      As advancements in Science into the Human Genome are made, these references are adjusted

      Each SNP has a reference position on our Genome, each build fine tunes so to speak their position.

      For instance SNP rs3094315 in Build 36 Raw Data is given the position of 742429 on Chromosome 1, in build 37 it is given the position of 752566.

      For Gedmatch you can use either Build 36 or Build 37 Data. Gedmatch uses Build 36 reference positions, but will convert Build 37 to Build 36 when build 37 is uploaded.

      FTDNA's chromosome Browser uses Build 36 positions also, so if want to look up position values in Raw Data you would open Build 36 Raw Data.

      Currently there is no real use for the end user for Build 37 Data, FTDNA uses it in their algorithms but results are displayed in Build 36 format (Chromosome browser Data)

      Edit
      If manually comparing 2 Raw Data files you would need to make sure they are both using the same build number.
      ie)manually comparing FTDNA raw data file with a 23andme Raw Data file. 23andme Raw Data is Build 37, so to manually compare your FTDNA Raw Data file to it, you would use your Build 37 Raw Data.
      Last edited by prairielad; 14 November 2015, 02:52 PM.

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      • #4
        Originally posted by prairielad View Post
        Each Build is a versions of human genome reference

        As advancements in Science into the Human Genome are made, these references are adjusted

        Each SNP has a reference position on our Genome, each build fine tunes so to speak their position.

        For instance SNP rs3094315 in Build 36 Raw Data is given the position of 742429 on Chromosome 1, in build 37 it is given the position of 752566.

        For Gedmatch you can use either Build 36 or Build 37 Data. Gedmatch uses Build 36 reference positions, but will convert Build 37 to Build 36 when build 37 is uploaded.

        FTDNA's chromosome Browser uses Build 36 positions also, so if want to look up position values in Raw Data you would open Build 36 Raw Data.

        Currently there is no real use for the end user for Build 37 Data, FTDNA uses it in their algorithms but results are displayed in Build 36 format (Chromosome browser Data)

        Edit
        If manually comparing 2 Raw Data files you would need to make sure they are both using the same build number.
        ie)manually comparing FTDNA raw data file with a 23andme Raw Data file. 23andme Raw Data is Build 37, so to manually compare your FTDNA Raw Data file to it, you would use your Build 37 Raw Data.
        Thank you for the explanation!

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