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question about GD, involving dsy 289-1 and 289-2

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  • question about GD, involving dsy 289-1 and 289-2

    Maybe somebody can help me with this. I found someone on ysearch whose GD from mine on 25 markers was given as 2. All of our markers are the same except for dys 289-1 and dys-2, which are 12 and 28 for me and 13 and 29 for the other person. But I thought that, effectively, 289-1 = 289a and 289-2 = 289a + 289b. In other words, this should really only be a GD of 1 since my dys 289-2 minus 289-1 is exactly the same as the other person's dys 289-2 minus 289-1. Or am I wrong about the relationship between dys 289-1 and dys 289-2?

  • #2
    Originally posted by garybook
    Maybe somebody can help me with this. I found someone on ysearch whose GD from mine on 25 markers was given as 2. All of our markers are the same except for dys 289-1 and dys-2, which are 12 and 28 for me and 13 and 29 for the other person. But I thought that, effectively, 289-1 = 289a and 289-2 = 289a + 289b. In other words, this should really only be a GD of 1 since my dys 289-2 minus 289-1 is exactly the same as the other person's dys 289-2 minus 289-1. Or am I wrong about the relationship between dys 289-1 and dys 289-2?
    Oops! Should have said "389" not "289".

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    • #3
      Originally posted by garybook
      Oops! Should have said "389" not "289".
      Mea culpa. I took another look at the comparison and found that at DYS 459B, I have an allele value of 10 and the other person (CZTZR) has a value of 9. Obviously, then, ysearch is not counting both the DYS 389I difference of +1 and the DYS 389II difference of +1, or the GD would be 3. But can someone tell me how significant a GD of 2 is on a comparison of 25 markers? I don't know this other person's surname, because it seems to be in some sort of code (016-B001) and I haven't yet gotten any response from CZTZR to my query. Can someone tell me the mutation rates of DYS 389I and DYS 459B?

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      • #4
        Originally posted by garybook
        Mea culpa. I took another look at the comparison and found that at DYS 459B, I have an allele value of 10 and the other person (CZTZR) has a value of 9. Obviously, then, ysearch is not counting both the DYS 389I difference of +1 and the DYS 389II difference of +1, or the GD would be 3. But can someone tell me how significant a GD of 2 is on a comparison of 25 markers? I don't know this other person's surname, because it seems to be in some sort of code (016-B001) and I haven't yet gotten any response from CZTZR to my query. Can someone tell me the mutation rates of DYS 389I and DYS 459B?
        389I has a mutation rate of 0.00186
        459 (including both a and b) has a mutation rate of 0.00132

        Both of those would be considered slow-mutating markers.

        Generally, I would say that a GD of 2 at 25 markers is enough to suggest a probable relationship between two people, but the fact that the differences are on slow-mutating markers, plus the fact that the surnames may not match, makes this conclusion more tentative. If you are able to get in touch with the person and convince him (and yourself) to upgrade to 37, or preferably 67, markers, that would be much more informative.

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