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Morley DNA Y-SNP sub-clade predictor

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  • Morley DNA Y-SNP sub-clade predictor

    I got introduced to the Morley site via Felix's Big Y Chrome add-on. It has given me things to think about. I had previously tested as DF27 +, so my subclade was R1b P312 DF27. My Big Y results did not test positive for the SNPs under D27.

    I ran my results on the Morley site, adding DF27 to my SNP list since Big Y did not list it.

    The MorleyDNA.com terminal subclade predictor provides a list of SNPs not accounted for in the prediction. I looked at 4 predictions and most of the not used SNPs were not used in all the predictions. 12 out of hundreds occur in some of the 4 variants and not others.

    One of the variants, R1b L150, fails to use all 12 of these and is pretty farfetched. Two fail to use 5 of these, R1B P312-DF27 and R1b L753. One, R1b CTS358,fails to use 2 of these.

    R1B P312-DF27 does not use CTS358, CTS7275, CTS8127, L753 and YSC0000081.

    R1b L753 does not use CTS358, CTS7275, CTS8127, YSC0000081 and DF27.

    R1b CTS358 does not use DF27 and L753. But the experimental tree has this under U152 and I am U152-. CTS7275, CTS8127 and YSC0000081 all go with CTS 358 in defining the subclade.

    I am not sure what to make of this. Just on parsimony, the CTS358 leaves fewer loose ends, but it does not fit with DF27 or U152 as the experimental tree is configured. Do any of the rest of you have something similar with these SNPs?

    John

  • #2
    R1b-L150 is a phylogenetically troublesome SNP.
    The "Author’s note" of the Febuary experimental tree says as much.
    The R1b-Z2105 portion of this tree is likely inaccurate, owing to the L150 backmutation soon after the initial mutation, and my confusion about how the reported results for this marker should be interpreted.
    Wonder what would happen if you just deleted L150?
    There are plenty of other SNPs that can be used to define subclades in this area. PF7558+, PF7562+ & PF7563+ for L23-, L150+ or Z2103-Z2110/CTS7822 for L23+, L150-.
    I'm R1b-M269+, L23+, L150+, Z2103+, Z2104+, Z2105+, Z2107-, Z2110/CTS7822-. L150 isn't necessary and may be misleading.

    Chris Morley (2014). An experimental computer-generated Y-chromosomal phylogeny, leveraging public Geno 2.0 results and the current ISOGG tree, version: 7 February 2014
    http://ytree.morleydna.com/experimental-phylogeny

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    • #3
      Originally posted by D.Clade View Post
      R1b-L150 is a phylogenetically troublesome SNP.
      The "Author’s note" of the February experimental tree says as much.

      Wonder what would happen if you just deleted L150?
      There are plenty of other SNPs that can be used to define subclades in this area. PF7558+, PF7562+ & PF7563+ for L23-, L150+ or Z2103-Z2110/CTS7822 for L23+, L150-.
      I'm R1b-M269+, L23+, L150+, Z2103+, Z2104+, Z2105+, Z2107-, Z2110/CTS7822-. L150 isn't necessary and may be misleading.

      Chris Morley (2014). An experimental computer-generated Y-chromosomal phylogeny, leveraging public Geno 2.0 results and the current ISOGG tree, version: 7 February 2014
      http://ytree.morleydna.com/experimental-phylogeny
      Thanks for responding. I know the L150 option is not really on the table. I probably should have ignored it.

      The DF27 and L753 are sort of paired, one does not include the other. CTS358 does not include either of those, but takes in 4 others.

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