H2a2a1 on Control Region

[nunofreiresilva]

Hello,

Having these mutations in CR (rCRS) 16519C 263G and 315.1C, knowing this would be h2a2a1, by testing the Coding Region will i have something completely different or just an extension of h2a2a1?

Thank you

[Melissa122]

Hello,

Having these mutations in CR (rCRS) 16519C 263G and 315.1C, knowing this would be h2a2a1, by testing the Coding Region will i have something completely different or just an extension of h2a2a1?

Thank you

Hi, I believe 16519c is pretty common as I have that as well. I also have the 263g and 315.1c but I am haplogroup h1ag. From what I read the 16519 is to be typically ignored since so many people have it , I don't think it is a defining mutation for grouping. However, I am still learning all of this and new to genetics and genealogy.

Another poster sent me this article below, it explains mutations. Hope it helps!

https://dna-explained.com/2019/05/23/mitochondrial-dna-part-2-what-do-those-numbers-mean/

[KATM]

If you upgrade to the Full Mitochondrial Sequence (FMS) test, it may refine your H2a2a1 branch to a possible subclade (sub-branch) of H2a2a1, but only if you have the mutations that define a subclade in your branch. It is possible that you may remain classified as H2a2a1.

So, your subclade after upgrading may be H2a2a1a, H2a2a1b, H2a2a1c, etc., but you will not be H2a3 or in some other major branch of H, and you will not be classified as in a different haplogroup (U, T, K, etc.).