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  • #46
    Originally posted by PeterLarsen View Post
    I know, the model suffers from approximately the same issues, we can't predict when a subclade is branched from its parent only by looking at the mutation counts.
    Yes, that is the flaw with this approach. You really need to estimate the age of each branch of the tree using an approach similar to Behar, or Soares. Mutations accumulate at highly variable rates so simply counting mutations is not very accurate for estimating ages.

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