New FMS match (U5b2b2)

[PDHOTLEN]

I've been notified that I have a new U5b2b2 FMS match. That is my second. This one has a genetic distance of 2, which probably indicates a common ancestor back in the Dark Age. He hasn't given any information about himself (yet?). He is not shown to match me in HVR1 or HVR1+HVR2. That could mean the "2" are in the control region, with the coding region matching me exactly.

[PDHOTLEN]

Lo and behold, I now have a third FMS match. This one is like the second, with a distance of 2. It also does not match my HVR1 or HVR2. It would be nice if they would join the U5b project. So I now have one match with a distance of one; and the two most recent matches with a distance of 2. The earliest one matches my HVR1 and HVR2, which means a coding region difference.

[1798]

Lo and behold, I now have a third FMS match. This one is like the second, with a distance of 2. It also does not match my HVR1 or HVR2. It would be nice if they would join the U5b project. So I now have one match with a distance of one; and the two most recent matches with a distance of 2. The earliest one matches my HVR1 and HVR2, which means a coding region difference.

A GD of one is equal to 3700 and two 7400 ybp.

[PDHOTLEN]

A GD of one is equal to 3700 and two 7400 ybp.

Thanks for the information. Common ancestor (with GD of 2) back in the Mesolithic, I guess.

[Rebekah Canada]

Hi,

It is not that bad. More like 1,500 years +/- 1,500 years per non-heteroplasmic difference.

A GD of one is equal to 3700 and two 7400 ybp.

[1798]

Thanks for the information. Common ancestor (with GD of 2) back in the Mesolithic, I guess.

I think that the general consensus is that MT Eve lived around 200,000 years ago and the average number of MT mutations are 55. My son has 55 and I have 66 so you could divide 200,000 by 55.
Maybe I have it wrong but some other posters may have a better idea.

[GST]

A GD of one is equal to 3700 and two 7400 ybp.

One mutation in the full mtDNA genome per 3700 years is a common estimate of the mutation rate, but assuming two people share a maternal ancestor 3700 years ago, and they both have the average of one mutation, then a GD of two would be 3700 years, so Rebekah's estimate seems about right. It is also important to take into account the uncertainty range - some 1 step matches could share a common maternal ancestor more than 1500 years while some could be much more recent than 1500 years. For people who don't have any 0-step matches, I think it is worthwhile contacting the 1 and 2 step matches. In most cases they probably won't share a recent common ancestor, but in some cases they might.

[Rebekah Canada]

Hi,

Yes, they might indeed. Especially if the mutation is on something fast moving like 309.1C.

...In most cases they probably won't share a recent common ancestor, but in some cases they might.

[PDHOTLEN]

I noticed today in looking at one of my rare HVR1+HVR2 matches that, in the list of surnames given, there appears to be 3 that are Native American, including a Cherokee reference. A couple of other surnames may point back to Long Island (early 1700s in my case). This could be cousins who went south during the 1700s with my line.

[rainbow]

PDHotlen, Congratulations!


I haven't received an email notification but I logged in yesterday and found out that I also have FMS matches now, two people who are H1c12 like me, and both are at a genetic distance of 1.

A GD of one is equal to 3700 and two 7400 ybp.

More like 1,500 years +/- 1,500 years per non-heteroplasmic difference.

Which one of these is correct?

[winner]

With no heteroplasmy

Hi,

It is not that bad. More like 1,500 years +/- 1,500 years per non-heteroplasmic difference.

I am not aware of heteroplasmy, in my results. I have an exact match at the FMS level. Do you think that we have a common ancestor in recent times, with no heteroplasmy?

[winner]

I have the mutation 309.1

Hi,

Yes, they might indeed. Especially if the mutation is on something fast moving like 309.1C.

I have this mutation(309.1C)as well.

[PDHOTLEN]

I just received my fourth FMS match (U5b2b2). Unfortunately, it is a genetic distance of 2. That would seem to be a long way back to a common ancestor; maybe centuries back.

[1798]

I just received my fourth FMS match (U5b2b2). Unfortunately, it is a genetic distance of 2. That would seem to be a long way back to a common ancestor; maybe centuries back.

It could be 7,400 ybp. The province of Leinster has the most U5 at 18% in the Isles.

[PDHOTLEN]

It could be 7,400 ybp. The province of Leinster has the most U5 at 18% in the Isles.

Who knows where my direct maternal ancestral line is really from? I psyched myself into believing that I have dukes and earls back there. But I could easily have gone astray in putting my deep tree together.