Here's a recent paper (originally published 4 April 2021) by Iain McDonald re: TMRCA calculation from Y chromosome STR and SNP data. I'm mostly interested in the SNP analysis, but I have to say the paper seems pretty poorly written to me.
In theory, Figure 4 should be constructed in an appropriate format, giving you all the information you need, in conjunction with the assumed mutation rate of 83 years at the 15 mbp resolution (page 3) and generation span of 35 years (page 12) to reperform the calculation whose results are summarized on page 19. Excel has defined standard functions for the Poisson distribution, etc., so this isn't rocket science. Just 26 individual data points to be aggregated into 6 brother clades.
But the reperformed results come nowhere near the TMRCA estimate reported by McDonald on page 19. Nowhere. Off by literally hundreds of years.
Doesn't anybody proofread these things before they get published? Granted, this is still better than the copy of the Adamov 2015 paper I was given, which was completely opaque as to the sampled data. But it's still ultimately useless unless the reported data are internally inconsistent. The Xue 2009 paper had a tiny sample size, but at least all the numbers checked against one another.
https://science.thewire.in/the-scien...them%20to%20be.
In theory, Figure 4 should be constructed in an appropriate format, giving you all the information you need, in conjunction with the assumed mutation rate of 83 years at the 15 mbp resolution (page 3) and generation span of 35 years (page 12) to reperform the calculation whose results are summarized on page 19. Excel has defined standard functions for the Poisson distribution, etc., so this isn't rocket science. Just 26 individual data points to be aggregated into 6 brother clades.
But the reperformed results come nowhere near the TMRCA estimate reported by McDonald on page 19. Nowhere. Off by literally hundreds of years.
Doesn't anybody proofread these things before they get published? Granted, this is still better than the copy of the Adamov 2015 paper I was given, which was completely opaque as to the sampled data. But it's still ultimately useless unless the reported data are internally inconsistent. The Xue 2009 paper had a tiny sample size, but at least all the numbers checked against one another.
https://science.thewire.in/the-scien...them%20to%20be.
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