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Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of

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  • Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of

    Sci Rep. 2014 Aug 13;4:6055. doi: 10.1038/srep06055.
    Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry.
    Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN.
    http://www.ncbi.nlm.nih.gov/pubmed/25116736
    free

    Abstract
    We investigated ancestry of 3,528 modern humans from 163 samples. We identified 19 ancestral components, with 94.4% of individuals showing mixed ancestry. After using whole genome sequences to correct for ascertainment biases in genome-wide genotype data, we dated the oldest divergence event to 140,000 years ago. We detected an Out-of-Africa migration 100,000-87,000 years ago, leading to peoples of the Americas, east and north Asia, and Oceania, followed by another migration 61,000-44,000 years ago, leading to peoples of the Caucasus, Europe, the Middle East, and south Asia. We dated eight divergence events to 33,000-20,000 years ago, coincident with the Last Glacial Maximum. We refined understanding of the ancestry of several ethno-linguistic groups, including African Americans, Ethiopians, the Kalash, Latin Americans, Mozabites, Pygmies, and Uygurs, as well as the CEU sample. Ubiquity of mixed ancestry emphasizes the importance of accounting for ancestry in history, forensics, and health.

  • #2
    Thank you, PNGarrison for all your postings concerning newest scientific research. It´s allways very interesting.

    :-) Petra

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    • #3
      Nice to know someone appreciates it. Thanks. (In order to get more views, I'm thinking of starting an argument about whether the sky is blue or green.

      Comment


      • #4
        I also read your posts, thanks for taking the time.

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        • #5
          Originally posted by PNGarrison View Post
          Nice to know someone appreciates it. Thanks. (In order to get more views, I'm thinking of starting an argument about whether the sky is blue or green.
          I have stopped looking myself since you are doing it

          W.

          P.S. It is a very nice touch that you started indicating which papers are free access

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