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  • mutations

    I just got my results today and it says I am in Haplogroup H in the mtdna test. I have two mutations on my HVR1: 16072T and 16519C. I can't find anyone else who has the 16072T mutation on the mitosearch website and I was wondering why.

    Can anyone shed some light on this for me because I am confused.


  • #2

    I am not an expert on H, but I didn't see any replies yet. As you say, there doesn't seem to be anybody else on mitosearch with 16072T (except one U person), and there is none in another database of complete sequences, mtdb. So it seems it is a very rare mutation indeed, which may be characteristic of your own particular lineage only.

    This ia potentially a very good thing: haplogroup H is extremely common, often people have many matches, most of which don't mean anything. But if in the future you find another H with 16072T, that may be a good sign of a possible recent common ancestry, since the mutation is so rare.

    Other than that, you have the extremely frequent 16519 mutation, so apart from the 16072, your profile falls perfectly into the very large and common European group of CRS with 16519, of which I bet mitosearch may have hundreds, if not thousands.

    This doesn't give enough information to assign you to a subgroup of haplogroup H (more than 20 subgroups have now been identified). If you are interested, you can find out by taking an H refinement test, or even, with other companies such as argusbio, the full mtdna test.