L3 mtDNA

[jmarshal]

Hello,

My HVR1 mutations of mtDNA are: 16048A, 16124C, 16223T, 16278T, 16362C.
HVR2 mutations: 73G, 150T, 185A, 189G, 315.1C, 523-, 524-.
HVR1 Haplogroup: L3. mathces an L3b.
Do not have the slightest idea what it means.

Can you tell me what this means?
Your help appreciated.
Junior Marshall

[cherylt4]

Hi, I'm L3 also, HVR 1 16093C, 16189C, 16223T, 16320T, and 16519C. HVR 2 73G, 150T, 195C, 263G, and 315.1C. There seems that there is much work to be done on African Haplogroups. Much of the work tha thas been done has been in West Africa. From my own research I believe that I may be L3e. Looking around for matches I come closest to people from the Carribean. let me know if you are able to find some relevant research Cheryl

[jmarshal]

Thank you Chyrl.
I have not done much research on the mtDNA haplogroup yet. But yes I should look at Africa to know more about my ancestors. I will like to know more about the L3 group. You are right. You have some one from the Caribbean. My parents are from the Caribbean but my maternal grandmother? Perhaps from Africa? Do not know.
Still looking, hoping for some clue.
Junior

[mlprince]

L3* and HVR1 Matching

Hello,

I found a study online of the mtDNA haplogroups and HVR1 mutations found in three populations from Cameroon. One of the persons in the study had a haplogroup of L3e2b, and their HVR1 mutations were: 172; 183C; 189; 223; 320. FTDNA says my haplogroup is L3*, and my HVR1 mutations are: 16172C; 16183C; 16189C; 16223T; 16320T; 16519C. Aside from the 16519C mutation, could the other numbers be considered a match to the results of Cameroon(ian?) person?

Am I really in haplogroup L3e2b? Or am I just confused? I'm thinking of purchasing the mtDNA refine test, but I'm unsure if doing so will clarify things or just create more questions.

I wish I understood more.

Meredith Prince

[shoshone]

African American with A haplotype

Hello,

I came back as being a (A) haplotype through my mitochondrial DNA Meaning Native American. I took two test. The first said I was as follows:

83% Sub-saharan African
13% European
4% Asian

My mutations were at 16223t, 16290t, 16291t, 16319a, 16362c, 16519c.

Any one with similar results? I found many matches from Mexican indians, Quatemala, choctaw, Seminole, and several Puerto Ricans, one with an exact match.

My family hails from North Carolina.

[Shyla]

L1a

This is my first post to this board.

My haplogroup=L1a Layla
HVR1=
16129A, 16148T, 16168T, 16172C, 16187T, 16188G, 16189C, 16223T,
16230G, 16311C, 16320T, 16519C

HVR2=
93G, 152C, 189C, 200G, 236C,247A, 263G, 309.1C, 315.1C, 522-, 523-

I need help in understanding the above.

My ancestors (My mother's side) are from the Bahamas.

Shyla

[vraatyah]

Hello,

My HVR1 mutations of mtDNA are: 16048A, 16124C, 16223T, 16278T, 16362C.
HVR2 mutations: 73G, 150T, 185A, 189G, 315.1C, 523-, 524-.
HVR1 Haplogroup: L3. mathces an L3b.

seems close to these ones (all are more likely to be in L3b)

African-American of FBI Laboratory
048-111-124-223-278-362 73-150-185-189-263-315.1C-523d-524d

Bioko (Mateu 1997)
048-124-223-234-240-278-362 N/A

African-American of FBI Laboratory
048-124-223-263-278 73-263-309.1C-315.1C

African-American of FBI Laboratory
048-124-223-278-284-362 73-150-185-189-263-315.1C-523d-524d

African-American of FBI Laboratory
048-124-223-278-284-362 73-150-185-189-263-315.1C

African-American of FBI Laboratory
048-124-223-278-284-362 73-150-185-189-263-315.1C-523d-524d-527N

African-American of FBI Laboratory
048-124-223-278-362 73-189-263-309.1C-315.1C-523d-524d

African-American of FBI Laboratory
048-124-223-278-362 73-150-185-189-263-315.1C-523d-524d

African-American of FBI Laboratory
048-124-223-278-362 73-185-189-249d-263-315.1C

African-American of FBI Laboratory
048-124-223-278-362 73-263-309.1C-315.1C

African-American of FBI Laboratory
048-124-223-278-362 73-185-189-249d-263-315.1C-523d-524d

African-American of FBI Laboratory
048-124-223-278-362-519 73-185-189-249d-263-315.1C-523d-524d

African Americans of Mc Lean
048-124-223-278-362 73-150-185-189-263-315.1C

[Electra]

My mutations were at 16223t, 16290t, 16291t, 16319a, 16362c, 16519c.

Any one with similar results?...

I have three similar HVR I mutations: 16223T, 16362C, 16519C

M-haplogroup. I'm originally from Central Asia.

I'm trying to find matches with mutations 16227G and 16278T

[Electra]

I made a mistake in my prevous message, haplogroup is M*

[dentate]

M* is a catch-all designation that includes many mtDNA lines from Asia that either are not yet further subclassified, or more likely, are not identifiable from the comparisons made by FTDNA in their database. The mtDNA haplogroups were originally defined by RFLP testing, which is very different from the sequencing of HVR-1 and HVR-2 that is being used here. Your M* assignment means that your particular mutations fall within those most likely to be found in the M* supergroup overall. "Vraatyah" is an expert on this and can probably assign you to a subgroup based on your mutations. My wife has some mutations similar to yours (1629A, 16223T, 16274A, 16278T, 16362C) and Vraatyah was able to show from his database that similar patterns of mutation have been assigned to mtDNA haplogroup G2. FTDNA simply called this M*, like yours. To be certain of the correct assignment would require RFLP testing (which I have not seen offered commercially) or complete mtDNA sequencing (which is offered by FTDNA but at a very high price, and would still need expert interpretation to be useful). My wife is from Buryatia. You, like my wife, can probably conclude that your maternal line has been in Central or East Asia for a very long time and is related to East Asians. Some mtDNA lines, and even more male NRY DNA lines in Central Asia, show more connections to Western/European/Paleocaucasoid (choose your favorite politically correct term) haplogroups.

[Electra]

Thank You for your reply.

I took time and searched the net for my sequences. I found out that I belong to the "twig" of M* tree-G2a. This small lineage is restricted to Central Asia-Kazakhs, Kyrgyzs, Uighurs, Tadjiks and Uzbeks, also some neighboring nations but in small quantities.

I'm Kazakh with some recent Turkic admixture from Volga region.

"G2a lineages seems to be also restricted to
Central Asia. This haplogroup characterized by the motif
16 223T, 16 227G, 16 278T, and 16 362C"

http://www.upf.es/cexs/recerca/bioevo/2004Jaume/JB2004-Comas-EJHG.pdf

Maybe I'm mistaken, but this is the closest and most plausible theory, which corresponds to my ethnical background.

[Electra]

Dentate: I browsed the topic where you posted your spouse'e DNA. I found a lot of similarities. In two articles about G2a-the only ones I have read so far, the authors indicated that this lineage is restricted to Central Asia, but in vraatyah's data base results I do not see anyone from Central Asians, rather Siberia.
"G2a is
highest among Central Asians (8.8%) and also above
3% in Tibetans and Ainu and rare or absent among
southern Chinese, Vietnamese, island Southeast Asians
(including Ryukyuans), and Siberians."

http://www.oxfordancestors.com/papers/mtDNA02%20LimbsTwigs.pdf

I also could not find 16519C mutation among the presented results.

[Electra]

I entered my sequences in data base of mtDNA in order to compare with existing samples:

http://www.genpat.uu.se/mtDB/

and got 16 results. 15 of them are Japanese and one is Georgian.

[vraatyah]

the authors indicated that this lineage is restricted to Central Asia

it isn't really so


Abazins of Nasidze 093-223-227-234-278-362 16024-16400
Ainu of Horai G2a 189-194-195-223-227-278-362-519 16048-16560
Ainu of Horai G2a 189-194-195-223-227-278-362-519 16048-16560
Azeri, Nasidze 2001 223-227-278-362 16024-16400
Bashkirs G2* 223-227-278-362 16024–16400
Bashkirs G2* 093-223-227-234-278-309-362 16024–16400
Bashkirs G2* 223-227-234-274-278-290-293C-362 16024–16400
Bashkirs G2* 223-227-234-274-278-290-362 16024–16400
Bashkirs G2* 223-227-278-362 16024–16400
Bashkirs G2* 223-227-278-362 16024–16400
Buryats of Derenko G2a 223-227-234-278-362 16000-16400
Buryats of Derenko G2a 223-227-274-278-362 16000-16400
Buryats of Derenko G2a 223-227-274-278-362 16000-16400
Buryats of Derenko G2a 223-227-278-362 16000-16400
Buryats of Derenko G2a 223-227-278-362 16000-16400
Buryats of Derenko G2a 189-223-227-278-362 16000-16400
Buryats of Pakendorf 223-227-278-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 223-227-278-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 223-227-278-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 223-227-278-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 223-227-278-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 223-227-234-278-309-362-390N-391N-399N 16000-16400
Buryats of Pakendorf 093-223-227-234-278-309-362 16000-16400
Buryats of Pakendorf 223-227-274-278-362 16000-16400
Buryats of Shimada 223-227-278-362-519 16001-16554
Buryats of Shimada 223-227-278-362-429A-430C 16001-16469
Buryats of Shimada 223-227-278-362 16001-16536
Buryats of Shimada 223-227-278-362-519 16001-16538
Buryats of Shimada 223-227-278-362 16001-16554
Buryats of Starikovskaya G2 220C-223-227-278-362 16000-16400
Buryats of Tajima 223-227-278-362 16048-16569
China (Liaoning, Han) of Yao MG2a 111-209-223-227-274-278-326-362 309.1C-315.1C 15996-16498; 29-408
China (Liaoning, Han) of Yao MG2a 111-223-227-278-362 309.1C-309.2C-315.1C 15996-16498; 29-408
China (Liaoning, Han) of Yao MG2a 189-194-223-227-278-311-362 309.1C-315.1C 15996-16498; 29-408
China (Qingdao, Han) of Yao MG2a 223-227-272-278-319-362-365 152-198-282-309.1C-315.1C 15996-16498; 29-408
China (Qingdao, Han) of Yao MG2a 209-223-227-234-278-309-362 152-315.1C 15996-16498; 29-408
China (Qingdao, Han) of Yao MG2a 223-227-278-311-362 152-315.1C 15996-16498; 29-408
China (Qinghai, Tu) of Yao MG2a 127T-129-223-227-278-319-362 16024-16401
China (Taiwan, Taiwanese) of Horai MG2a 129-223-227-272-278-319-362 16048-16560
China (Taiwan, Taiwanese) of Horai MG2a 051-172-223-227-272-278-311-319-362-519 16048-16560
China (Wuhan, Han) of Yao MG2a 223-227-262-278-362 152-309.1C-315.1C 15996-16498; 29-408
China (Xinjiang, Han) of Yao MG2a 189-223-227-256-278-362 153-195-309.1C-315.1C 15996-16498; 29-408
China (Xinjiang, Uighur) of Yao MG2a 093-223-227-278-362 16024-16401
China (Xinjiang, Uighur) of Yao MG2a 169-223-227-262-278-294-318-362 16024-16401
China (Xinjiang, Uighur) of Yao MG2a 223-227-278-362 16024-16401
China (Xinjiang, Uighur) of Yao MG2a 093-223-227-234-278-309-362 16024-16401
China (Xinjiang, Uighur) of Yao MG2a 223-227-278-293C-362 16024-16401
China Han (Wen 2004) 223-227-278-362 16024-16383
China Han (Wen 2004) 223-227-278-362 16024-16383
China Han (Wen 2004) 223-227-278-362 16024-16383
China Han (Wen 2004) 223-227-278-362 16024-16383
China Han (Wen 2004) 223-227-278-326T-362 16024-16383
China Han (Wen 2004) 183d-223-227-278-362 16024-16383
China Han (Wen 2004) 093-223-227-234-244-278-309-362 16024-16383
China Han (Wen 2004) 223-227-272-278-319-362 16024-16383
China Han (Wen 2004) 223-227-278-362 16024-16383
China Han Changsha (Oota 2002) 223-227-278-294-362 16001-16400
China Han Changsha (Oota 2002) 223-227-278-355-362 16015-16400
China Han Changsha (Oota 2002) 223-227-272-278-319-362 16011-16400
China Han Changsha (Oota 2002) 182N-183N-184N-185N-186N-187N-188N-189N-190N-191N-192N-193N-194N-223-227-234-278-362 16010-16396
China Han Changsha (Oota 2002) 093-147-223-227-234-278-309-362 16002-16400
China, S., Vigilant 1991 086-172-223-227-272-278-319-362 16024-16394
China/Taiwan of FBI Laboratory 172-223-227-272-278-319-362-519 73-152-263-309.1C-315.1C-489 16024-16569; 1-576
China/Taiwan of FBI Laboratory 223-227-278-362 73-263-295N-297N-309.1C-309.2C-315.1C-489 16024-16569; 1-576
China/Taiwan of FBI Laboratory 114N-223-227-278-362 73-199-204-263-309.1C-309.2C-315.1C-489 16024-16569; 1-576
Chinese from Taiwan G2a 172-223-227-272-278-301-319-362
Chinese from Taiwan G2a 223-227-272-278-319-362
Chinese Shandong of Yao G2a 223-227-278-362 73-152-263-315.1C 16000–16569; 1-407
Daur G2a 223-227-234-278-362 16001-16497
Daur G2a 223-227-243G-278-293C-362 16001-16497
Germans Lower Saxony G2* 169-223-227-262-278-294-318-362 16041-16365
Hong Kong of Horai 129-223-227-272-278-319-362 CRS 16048-16569; 1-41
Hong Kong of Horai 051-172-223-227-272-278-311-319-362-519 CRS 16048-16569; 1-41
Huis of Yao G2a 223-227-234-278-362 N/A 16001-16497
Huis of Yao G2a 223-227-278-362 N/A 16001-16497
India (Andhra Pradesh, Andhra Pradesh) of Bamshad MG2a 086-172-189-223-227-278-362 16024-16383
India (Andhra Pradesh, Andhra Pradesh) of Bamshad MG2a 086-172-189-223-227-278-362 16024-16383
India (Sri Lanka, Moor) of Metspalu MG2a 086-172-189-223-227-278-362 16024-16400
Iranians (southwest, Iran) of Metspalu MG2a 086-129-172-223-227-278-362 16024-16400
Iranians (southwest, Iran) of Metspalu MG2a 086-172-223-227-278-362 16024-16400

[vraatyah]

Japan of Armed Forces DNA Lab 093-183C-189-194-195-223-227-278-362 73-263-309.1C-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 189-194-195-223-227-278-362 73-150-263-309.1C-309.2C-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 183C-189-194C-195-223-227-278-362 73-263-309.1C-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 189-194-195-223-227-278-362 73-263-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 182C-183C-189-194-195-223-227-278-362 73-263-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 183C-189-194-195-223-227-278-311-362 73-263-315.1C 16024-16365; 73-340
Japan of Armed Forces DNA Lab 223-227-234-278-309-362 73-152-263-309.1C-315.1C 16024-16365; 73-340
Japan of Horai 183d-189-193.1C-193.2C-223-227-278-362-519 CRS 16048-16569; 1-41
Japan of Seo 093-223-227-234-278-309-362 73-146-152-263-315.1C 16024-16399; 56-373
Japanese from Gifu G2a 223-227-278-362
Japanese from Gifu G2a 189-193G-194C-223-227-278-362
Japanese of Imaizumi G2a 093-183C-189-194-195-223-227-278-362 73-263-309.1C-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 182C-183C-189-194-195-223-227-278-362 73-263-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 183C-189-194-195-223-227-278-311-362 73-263-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 183C-189-194C-195-223-227-278-362 73-263-309.1C-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 189-194-195-223-227-278-362 73-263-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 189-194-195-223-227-278-362 73-150-263-309.1C-309.2C-315.1C 16024-16365; 73-340
Japanese of Imaizumi G2a 223-227-234-278-309-362 73-152-263-309.1C-315.1C 16024-16365; 73-340
Japanese of Nishimaki G2a 189-194-195-223-227-278-362
Japanese of Tanaka G2a1a 183C-189-193.1C-223-227-278-362-519 73-263-315.1T-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194C-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka D4b 223-227-278-362 73-199-263-309.1C-315.1C-489-514d-515d 16000-16569; 1-576
Japanese of Tanaka G2a1a 093-183C-189-194C-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 223-227-234-278-362 73-152-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 223-227-234-278-362 73-152-263-315.1C-316-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 183C-189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 223-227-234-278-362 73-152-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 093-189-194-223-227-278-362-519 73-263-309.1C-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 223-227-278-362 73-146-207-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 183C-189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 093-223-227-278-362 73-146-207-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 189-194-195-223-227-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 094-189-194C-195-223-227-260-278-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 183C-189-194-195-223-227-278-362-519 73-263-309.1C-309.2C-315.1C-489 16000-16569; 1-576
Japanese of Tanaka G2a1a 183C-189-194-195-223-227-278-311-362-519 73-263-315.1C-489 16000-16569; 1-576
Japanese(Honshu) of Tajima 223-227-234-278-362 16048-16569
Japanese(Honshu) of Tajima 183C-189-193.1C-223-227-278-362-519 16048-16569
Japanese(Honshu) of Tajima 189-189.1A-194-195-223-227-278-362-519 16048-16569
Japanese(Kyushu) of Tajima 183C-189-223-227-278-362-519 16048-16569