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Hi -first some info of hopefully general use, at least to other "T's". I extracted all the T's from the mitosearch database: there are 71 such people as of Dec 26, 2004. If the current estimate that "Taras" make up nearly 10% of native Europeans, then this suggests (assuming randomness and forgetting about small numbers) there are approximately 710 European samples on the database. Not very many, especially given the Y chromosome database nears 20,000 I am told, though perhaps not too bad given its fairly new. The oxfordancestry database seems to have even less Europeans on the mitochondrial database, though they claim that "soon" they will make availble 10,000 samples that have been collected from various research studies (though not all european).
The breakdown of the number of people that have the different T subgroups on the mitosearch database are as follows:
T 12
T* 6
T1 23
T2 23
T3 3
T4 2
T5 2
According the data provided by Vincent McCauley, the criteria used in the Richards et al. 2000 study was that to be in Haplogroup T, one has to have mutations at 126 and 294. That is, all the different T sub groups must have those two mutations to be classified as T. (This info is availalbe on-line- go to the website linked in the 4 page pdf file that comes with your on-line results. The pdf file is under the link "understanding your results") (side issue: Does this imply that only Ts have both of these mutations? What about just one of the mutations? Is it in any way part of the criterion for any other Haplogroup?) In addition, the criterion for T5 subgroup is a mutation at 153.
I mention T5 because my recent data (I was in batch 99- just got my results) was classified as Haplogroup T5, and I do have all three of those mutations (126, 153, 294).
In addition, I have 4 more mutations in the HVRI region for a total of 7 mutations, and I'm not quite sure yet what to make of them. The additional 4 mutations are at 114, 192, 221, and 519.
The only other person who is also a T5 on the mitosearch database also has a mutation at 519 (in addition to the 3 required mutations), but he has none of the other additional 3 mutations that I have and he has a mutation at location 292 which I don't have.
I checked the rest of the McCauley database (the data that went into the 2000 study), and there is no exact match to my 7 mutations, or even to 6 of them.
Best I can piece together, thinking out loud, is the following. I share in common with the other 70 individuals maternal clan mother Tara, who was believed to live approximately 17,000 years ago in Italy. She is the maternal ancestor of the 70 of us, more than 500 generations ago. Sometime between 17,000 and 10, 000 years ago (whenever T5 is beleived to occur) , our lines (mine and the other 69) go seperate ways, except for one of those individuals. At some point after T5 (let's say that was 13,500 years ago), probably rather quickly, my line goes a seperate way from that other (70th)T5 indiviudal's line. I say rather quickly because I still have 3 more mutations to accumulate, which doesn't leave much time!
I guess the estimaste that there is 1 mutation every 10,000 years is obviously just an average. If there's a high variabilty to that estimate, I would think that makes it very hard to determine the timelines.
One other detail is that i tried looking up my other mutations that aren't part of a typical tara pattern - so far I come up with those matching "helena"-but that's not suprising, since for that search i'm putting in one mutation at a time, and since helena is the cambridge reference standard, it's not suprising that only 1 mutation wojjld turn up helenas most often, especially since they make up 40% of eureopeans.
Any comments on my pattern of 7 mutations most welcome (to summarize, my pattern for HVRI is 114T, 126C, 153A, 192T, 221T, 294T, 519C). Hard to know if this is an unusual pattern given so few people on the database. (If it is unusual, I guess this suggests than if I ever find an exact match, the odds are probably higher than the average that we share a reasonably near ancestor). Otherr comments on taras, or on the time line or on good articles to read also most welcome - if i seem to get anything wrong above please also let me know that too. (I also got the 2nd control region analyzed, but it deons't look like i need a high resolution analysis quite yet...though quick scan suggests i may have more matches to that region than to the main control region).
guess that's it for now.
The breakdown of the number of people that have the different T subgroups on the mitosearch database are as follows:
T 12
T* 6
T1 23
T2 23
T3 3
T4 2
T5 2
According the data provided by Vincent McCauley, the criteria used in the Richards et al. 2000 study was that to be in Haplogroup T, one has to have mutations at 126 and 294. That is, all the different T sub groups must have those two mutations to be classified as T. (This info is availalbe on-line- go to the website linked in the 4 page pdf file that comes with your on-line results. The pdf file is under the link "understanding your results") (side issue: Does this imply that only Ts have both of these mutations? What about just one of the mutations? Is it in any way part of the criterion for any other Haplogroup?) In addition, the criterion for T5 subgroup is a mutation at 153.
I mention T5 because my recent data (I was in batch 99- just got my results) was classified as Haplogroup T5, and I do have all three of those mutations (126, 153, 294).
In addition, I have 4 more mutations in the HVRI region for a total of 7 mutations, and I'm not quite sure yet what to make of them. The additional 4 mutations are at 114, 192, 221, and 519.
The only other person who is also a T5 on the mitosearch database also has a mutation at 519 (in addition to the 3 required mutations), but he has none of the other additional 3 mutations that I have and he has a mutation at location 292 which I don't have.
I checked the rest of the McCauley database (the data that went into the 2000 study), and there is no exact match to my 7 mutations, or even to 6 of them.
Best I can piece together, thinking out loud, is the following. I share in common with the other 70 individuals maternal clan mother Tara, who was believed to live approximately 17,000 years ago in Italy. She is the maternal ancestor of the 70 of us, more than 500 generations ago. Sometime between 17,000 and 10, 000 years ago (whenever T5 is beleived to occur) , our lines (mine and the other 69) go seperate ways, except for one of those individuals. At some point after T5 (let's say that was 13,500 years ago), probably rather quickly, my line goes a seperate way from that other (70th)T5 indiviudal's line. I say rather quickly because I still have 3 more mutations to accumulate, which doesn't leave much time!
I guess the estimaste that there is 1 mutation every 10,000 years is obviously just an average. If there's a high variabilty to that estimate, I would think that makes it very hard to determine the timelines.
One other detail is that i tried looking up my other mutations that aren't part of a typical tara pattern - so far I come up with those matching "helena"-but that's not suprising, since for that search i'm putting in one mutation at a time, and since helena is the cambridge reference standard, it's not suprising that only 1 mutation wojjld turn up helenas most often, especially since they make up 40% of eureopeans.
Any comments on my pattern of 7 mutations most welcome (to summarize, my pattern for HVRI is 114T, 126C, 153A, 192T, 221T, 294T, 519C). Hard to know if this is an unusual pattern given so few people on the database. (If it is unusual, I guess this suggests than if I ever find an exact match, the odds are probably higher than the average that we share a reasonably near ancestor). Otherr comments on taras, or on the time line or on good articles to read also most welcome - if i seem to get anything wrong above please also let me know that too. (I also got the 2nd control region analyzed, but it deons't look like i need a high resolution analysis quite yet...though quick scan suggests i may have more matches to that region than to the main control region).
guess that's it for now.
)
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