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mutations - ancestral version

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  • mutations - ancestral version

    hello,

    519C, 263G, 309.1C, 309.2C, 315.1C
    many times are said to be the "ancestral version" of a haplotype.
    my question: how old are these mutations?

    best regards
    mrh

  • #2
    Apart from 16519, these are not mutations. As you say, the are the ancestral values.

    The results only say that you differ from CRS in those SNPs, but they don't say who has the original values and who has the mutation. In this case, it is CRS who has a mutation, and you have the original values.

    As for when CRS had these mutations, they must be pretty recent, perhaps a few thousand years, because these are found only in the sub-branch where CRS is.

    cacio

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    • #3
      thank you for your answer, cacio

      but what about 519C? what is different with that ...

      and another question: what exactly is a snp?

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      • #4
        Originally posted by mrh View Post
        what exactly is a snp?
        http://en.wikipedia.org/wiki/Single-...e_polymorphism

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        • #5
          Regarding your question about 16519, it is a very volatile position, it is found in many haplogroups independently, and it probably switches back and forth as well. So it is usually ignored when drawing a haplogroup tree. And it's also basically impossible to say what was the ancestral value.

          cacio

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          • #6
            Actually, if you go back through this chain of ancestors, you should be able to figure out the ancestral version of most markers:

            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.

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            • #7
              RE that danged 519

              Originally posted by cacio View Post
              Regarding your question about 16519, it is a very volatile position, it is found in many haplogroups independently, and it probably switches back and forth as well. So it is usually ignored when drawing a haplogroup tree. And it's also basically impossible to say what was the ancestral value.

              cacio
              I'm often lumped with another group for convenience, and it irks me.

              My HVR1: 270 & 519
              Other group HVR1: 270 all by itself.

              That makes the ancestral origins page, etc., less elucidating.

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