23andme

[darroll]

This gets a little old.
If I wanted to test with another place, I would go there.
Getting a little tired of the crude advertisments.
I could also go to the Indian site and be a Indian chief.

[darroll]

You can't go by that.
Some bad genes never get turned on by the body.
Snake Oil, want to buy a gallon?

[rainbow]

So maybe my restless leg syndrome and sprinter ability will help save me from venous thromboembolism.

[rainbow]

I just found the traits section of my 23andme.

I have AA for norovirus.
"Resistant to infection by the most common strain of norovirus.
Norovirus resistance is highly heritable. If you have two copies of the A version of this SNP, you lack a functioning FUT2 gene and are most likely resistant to the virus. Genetic changes other than the SNP 23andMe reports may allow people to be resistant even if they do not have the AA genotype." That surprises me. But in the other section it says I have a higher risk of stomach cancer, and restless legs syndrome.


Likely sprinter. CC. Two working copies of alpha-actinin-3 in fast-twitch muscle fiber. Many world-class sprinters and some endurance athletes have this genotype.
Likely blue eyes. GG In Europeans, 72% chance of blue eyes; 27% chance of green eyes; 1% chance of brown eyes.
wet ear wax, can taste bitter, does not flush (?!?)(I am somewhat florid all the time, blush very easily), and likely tolerant (for lactose)



increased sensitivity to Warfarin.




Carrier Staus Variant Present for two categories:
hemochromotosis carrier. Carrier for the mild HH-associated H63D mutation; no increased risk for iron overload.

Most likely does not have Tay-Sachs. Will have false positive result for Tay-Sachs blood test that measures hexosaminidase A activity.



elevated risk for:
Chron's disease 2.9%
Venous Thromboembolism 28%
Psoriasis 20%
Age-related macular degeneration 9.5%
Type 2 diabetes 23%
Atrial fibrillation 20%

[tomcat]

Try Me

If anyone following this thread has 23andMe results and a reason to believe they might relate to either of the ancestries in my signature, please drop me a line at 23andMe. Same nickname.

[Carolyn1955]

Found it! Thanks

Go to www.23andme.com/you/relfinder and click on the appropriate box.

[MMaddi]

Hi, I would opt in if I knew where it was on the website. I've not been able to find the option to opt in to the Relative Finder feature.
Carolyn

Go to www.23andme.com/you/relfinder and click on the appropriate box.

[Carolyn1955]

Hi, I would opt in if I knew where it was on the website. I've not been able to find the option to opt in to the Relative Finder feature.
Carolyn

Greetings folks! I can't imagine that anyone here hasn't opted in to the Relative Finder feature, but in case you haven't please do. I've got 204 potential cousins (4th-distant), but only 9 have opted in. I'm sharing with 7 of those - and may have helped 2 of them to look for potential genealogical relationships even though they "missed the bar."

I'm hoping to find some of those possible 4th cousins specifically. Take care,
Sonia

[Sonia]

Opt In to Relative Finder

Greetings folks! I can't imagine that anyone here hasn't opted in to the Relative Finder feature, but in case you haven't please do. I've got 204 potential cousins (4th-distant), but only 9 have opted in. I'm sharing with 7 of those - and may have helped 2 of them to look for potential genealogical relationships even though they "missed the bar."

I'm hoping to find some of those possible 4th cousins specifically. Take care,
Sonia

[DKF]

Rainbow,

What about finding and compares with people who are in the same or similar boat as you. I`m talking about the ones who do have Asian/Native American ancestry but receives 100% European for their test. They are there, go to 23andMe look through the threads you should find them. Who knows you maybe within their cluster (group) if that the case, you may share ancestry with then also. Maybe you`re the one of many important puzzle to solve this mystery on How so many people have 100% European DNA with no hint of Native American ancestry. I bet it have something to do with the way the company test DNA compares to other companies and the Native American woman Ancestry Painting which is half European.

I was told my family have Native American Ancestry from two branches of the Family tree. Here a link http://spittoon.23andme.com/2008/06/...stry-painting/ and comment from it,

You are correct that the diagram does include
Asian (or Native American) ancestry from both the maternal and
paternal lines in several locations across Dr King

Gene, I expanded on what you said with a few other details. Thanks for getting me to think more deeply about this business. Here follows what I said on the Rootsweb List:

"For some time I have been examining the Ancestry Paintings of the people who I share findings with - over 100. Most are 100% European, but perhaps a third have some degree of "Asian" and / or African blocks showing in their "painting".

Something that was said in another forum prompted me to go to the painting of Dr. Roy King (a prominent American of African - American heritage) and examine each chromosome closely. The painting and interpretation is given here:

http://spittoon.23andme.com/2008/06/13/a-beautiful-ancestry-painting/

What is odd (and Dr. Ann Turner picked up on this before I noted it) is that many if not most of the large number of Asian blocks extend the full width of the chromosome. This makes absolutely no sense from any genetically oriented explanation I can come up with. Even fully siblings would not show this degree of correspondence (or exact placement of small haploblocks). Some of these blocks appeear to be over 10 Mb and others cannot be over 1 Mb - but how can they extend beyond the half way point on any of the chromosomes. Something is clearly amiss.

The second factor is that on any person with majority European ancestry that I have seen, there will be some (e.g., two) blocks of say 5 Mb (it is impossible to tell the exact size since the dimensions are not given nor are the start - stop positions). None go over the half way point to extend across the width of the chromosome. Why are there very narrow blocks in Dr. King's painting, but never in the large number of paintings with majority European that I have seen, is any block that small, even remotely so, shown - never.

I have said all along that there is a bias inherent in the algorith. On the first pass it determines the major parameters of the genomic ancestry structure. Then comes the if - then components. Clearly any Asian like blocks in someone with African and Asian are allowed through the filter and "painted". However if the algorithm has determined "European" a different set of criteria appear to be applied - my guess is if less than 10 Mb (perhaps 5 Mb - translated into cM equivalent) assume false positive and attribute to "European". I am not sure all of the orange is really Asian or Native American - but more likely misclassified African - hence the block extending across the chromosome. The 23andMe company representative reports that these findings are characteristic of the San - the resemblance to East Asians (not seen in the Nigerians used as reference samples in 23andMe).

The bottom line is that due to fear of false positive in an otherwise blue (European) background it is necessary to have a much larger block than if it is found that your ancestry is a mosaic of all three groups. Or so it would seem.

I am only giving an opinion here, but there is not a shadow of a doubt in my mind that the algorithm 23andMe employs classifies people on the basis of criteria that depend on the Gestalt of the genomic structure, and us primarily "blue folk" are never going to see the micro blocks that are portrayed in Dr. King's painting. However the timely presentation of the Browning and Hon team noted in an earlier posting today speak elegantly to this issue. Identical by descent can be teased out even at the 1 Mb level - but it will be necessary to use a program such as BEAGLE and to broaden the reference samples (the Han simply will not cut it as a reference group for those of us who wish to find evidence of Native North American ancestry - ok, I am a broken record on this point)".

[DKF]

Did Tribes match you to African populations?

If someone is, in this instance, < 1% African with two relatively small African blocks on 22 pairs of autosomes could we expect a test that uses a grand total of 21 markers to say anything about the minority ancestry other than in established groups such as Mexican Mestizo (still here there would be vast diversity here such that false positives and false negatives would be rampant).

[tomcat]

... DNATribes said my STR profile was consistent with approximately 1/8 Native American ancestry, with 1/8 to 1/4 Native American ancestry not excluded. DNAPrint said I was 17%. 23andme says none at all. I think 2 out of 3 wins.
And I don't have African ancestry.

Did Tribes match you to African populations?

[tomcat]

Before I got my results I had thought of finding and comparing with people who got an Asian score but are North American Indian to see what we have in common. But since I didn't even get an Asian score there is no point of finding and sharing...

Finding is a problem.

[rainbow]

Rainbow,
I read some where the African DNA could be something else other then Sub-Saharan Africa it could be DNATribes North African matches or something else. As far your Asian DNA, I uses 23andMe look around i found out they are quiet tight giving out Asian DNA with those who have distance Asian/Native American Ancestry compares to DecodeMe. What i`m trying to say there many people uses 23andMe with undetectable Asian ancestry.

Yes, my July (?) top match was to North Africa. DNATribes matched me to every single Indo-Europeam world region category they have. They say my top two native matches are Syria and Morocco. But they also told DKF that his top matches were Yemen and Saudi, if I remember right.
I have multiple Iberian (Portugal etc) and Flemish top 20 matches.

[rainbow]

Before I got my results I had thought of finding and comparing with people who got an Asian score but are North American Indian to see what we have in common. But since I didn't even get an Asian score there is no point of finding and sharing.
I downloaded all the data to my Dell but discovered tonight when I tried to read it that it isn't readable. At first I thought, "It's in Greek!", but it's actually in some code of English letters and symbols and numbers. I will have to download it again another day.