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X-STRs test and the Szibor paper

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  • X-STRs test and the Szibor paper

    Hello,

    While I was reading the scientific paper (commonly called "The Szibor paper) which title is:

    < DXS10079, DXS10074 and DXS10075 are STRs located within a 280-kb region of Xq12 and provide stable haplotypes useful for complex kinship cases>
    By Hering et al 2005

    I found something strange.

    In the table 7 there are the 35 most frequent haplotypes in the East German population. There is also the number (N) of individuals associated with those haplotypes.

    I also got the whole database (the 172 haplotypes found in that population).
    I tried to find, in the whole database, some haplotypes that are found in table 7 but they were not there ! Especially haplotypes that have the result DXS10074= 7 or 8. I found that strange so I decided to compare some of the most frequent haplotypes.

    E.G.:

    Table 7 (DXS10079-74-75).

    - 20-16-17 40 indivudials
    - 19-17-17 29 individuals
    - 20-17-17 28 individuals
    - 20-17-18 25 individuals

    In the whole database (supplementary material) I found that the only haplotype "associated" with 40 individuals was DXS10079-74-75= 20-18-17 and not 20-16-17 !

    Could it be due to an error ?

    For those three other frequent haplotypes it is the same thing.
    In the whole database the only hapl. associated with 29, 28 and 25 individuals are:
    DXS10079-74-75
    19-19-17
    20-19-17
    20-19-18

    Between the table 7 and the whole database (172 haplotypes) there is no change for DXS10079 and DXS10075. However DXS10074 "slid" of two digits in the whole database (+2).
    It seems to be also the case for the other haplotypes.

    Question 1)

    - Why ?

    Question 2)

    - So, when we compare our Ft-DNA X-STRs results with the haplotypes in that paper what happens ? Do we have to add 2 digits to DXS10074 in our Ft-DNA results when we compare them to that paper ?

    Thanks

    Nordvarg

  • #2
    Link to links to more papers. This outfit sells the forensic kit so they may be good place to check for new papers.

    http://en.biotype.de/index.php?optio...d=52&Itemid=56

    Comment


    • #3
      Nordvarg,

      Contact Szibor and/or see if an Errata has been published to his paper.

      Comment


      • #4
        Originally posted by Nordvarg
        ...
        Question 2)

        - So, when we compare our Ft-DNA X-STRs results with the haplotypes in that paper what happens ? Do we have to add 2 digits to DXS10074 in our Ft-DNA results when we compare them to that paper ?

        ...
        The question is; which is correct, the whole database or the paper tables?

        Comment


        • #5
          Has there been a clarification of this discrepancy?

          Comment

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