Tribes scores

[Maria_W]

20 top scores.

3-19-07 top scores are:
1. Bucharest, Romania 320.64(This has been my top score for the last 6 reports or so)
2. Germany 218.33
3. Czech Republic 196.28
4. Northern Ireland 160.71
5. Podlasie, Northeast Poland 144.85
6. Caucasian 148.48
7. Italy 137.73
8. Denmark 135.87
9. South Poland 128.87
10. Caucasian 104.89
11. Bosian 101.46
12. Caucasian 95.66
13. Southeast Poland 94.38
14. Caucasian Northern Territory, Australia 86.75
15. Caucasian (USA) 85.30
16. Caucasian (Indiana) 81.28
17. Caucasain (USA) 77.63
18. Flemish 77.01
19. Belarus 72.94
20. Vienna, Austria 71.58

Maria

[Maria_W]

Top population.

Actually my score dropped 200 points 520-320 from 1-15-07 for Bucharest, Romania. I just meant Romania has been my top population for quit some time now.
Maria

[tomcat]

Admixture analysis is of compelling interest to geneticists. There are severals ways to compute it and several marker sets employed.
...
It is all way over my head. But if someone can figure this out and devise a successful routine they would have a business....

Maybe, one day, Tribes will allow programmatic use of their extraordinary database of allele frequencies. You write the program to make use of that data and they run it. You get the results.

Omnipop may never catch up.

[Sonia]

Squeaky Wheels...

Admixture analysis is of compelling interest to geneticists. There are severals ways to compute it and several marker sets employed.

"Informativeness of the CODIS STR Loci for Admixture Analysis"
Jill S. Barnholtz-Sloan, 1 Ph.D.; Carrie L. Pfaff,2 Ph.D.; Ranajit Chakraborty,3 Ph.D.; and Jeffrey C. Long, 2 Ph.D.

There is even some software online.

'LEA' at www.rubic.rdg.ac.uk/~mab/software.html
'ADMIX 1.0' at https://www.web.unife.it/progetti/ge...rgio_soft.html
'ADMIX2.0' at https://www.web.unife.it/progetti/ge.../admix2_0.html
'ADMIX95' at www.genetica.fmed.edu.uy/software.htm
'ADMIXMAP' at www.Ishtm.ac.uk/eu/genetics/admix.html
'STRUCTURE' at www.pritch.bsd.chicago.edu/

It is all way over my head. But if someone can figure this out and devise a successful routine they would have a business.

Well Tom,
If you can't figure out how to use these, then there's not much hope for me as I'm sort of a "Plug and Play" with the allele values type. Perhaps if you come up with some useful programming, then the Tribes folks will make you a partner, run your program, give you shares, and free updates for life

Thanks also, Noaide for the heads up on the article and the programs. I think with the pharmaceutical industry realizing that there may be differences in treatment plans based on genetic make-up, some oil will start to flow on this wheel.

[kelly40]

Surprised by Ancestry by DNA result..

After receiving the results from the Tribes analysis shown below, I was surprised to get a result of 92% European and 8% Sub Saharan African result from Ancestry by DNA. Either could be correct considering the unknowns in the family tree, but it seems weird that they are so different. At least to me they seem to be. I don't have any Sub Saharan African in the Tribes report at all. Does anyone know if they have different definitions of what Sub Saharan Africa is?


High Res Global from DNAtribes:

European Cape Town, South Africa 394.7
Andulusia Spain 370.6
Veneto, Italy 300.2
Catanzaro, Italy 296.2
East Indian (Canada) 230.6
Toscana, Italy 219.1
Toscana, Italy 189.8
Santa Catarina, Brazil 181.3
Lombardia, Italy 179.1
Dundee, Scottland 166.0
Basque (Alava, Spain) 160.0
Greece 150.1
Italy 141.5
Switzerland 137.8
Ibiza Island, Balearic Archipelago 134.2
Caucasian 116.5
Caucasian 114.2
Dusseldorf, Germany 113.3
Greece 110.7
Marche, Italy 109.0

The High Res World came back as:

Mediterranean 98.67
Northwest European 63.64
Asia Minor 56.06
Arabian 23.58
Eastern European 10.41
India 9.52
Mestizo 8.56
North India 0.66
Finno-Ugrian 0.23
India Tribal .06
Mongolian 0.05
Australian 0.03
North African 0.01

Thanks for any advice anyone has regarding how to interpret this,

Kelly

[jaranta]

Sub-Saharan African

Kelly,
My Ancestry by DNA test also showed a small amount of Sub-Sah. African (5%). Like yours, my Tribes test did not return results for any S-S Afric. country. Again, like you, I also received a fairly strong score for Mestizo in World Region Match. DNA Tribes defines "Mestizo" as Native American blended with European and African. So I think that my Mestizo result is reflecting my small percentage of African ancestry.
Did you suspect that you had any African ancestry before your Ancestry by DNA test? Mine was a complete surprise. My other results were: 85% Euro, 5% Native Amer., 5% East Asian, 5% Sub-Sah. African. Since some of my percentages are pretty small and possibly invalid, I'm planning to retake the Ancestry by DNA test when 3.0 (or whatever the next version is called) comes out.
Judy

After receiving the results from the Tribes analysis shown below, I was surprised to get a result of 92% European and 8% Sub Saharan African result from Ancestry by DNA. Either could be correct considering the unknowns in the family tree, but it seems weird that they are so different. At least to me they seem to be. I don't have any Sub Saharan African in the Tribes report at all. Does anyone know if they have different definitions of what Sub Saharan Africa is?


High Res Global from DNAtribes:

European Cape Town, South Africa 394.7
Andulusia Spain 370.6
Veneto, Italy 300.2
Catanzaro, Italy 296.2
East Indian (Canada) 230.6
Toscana, Italy 219.1
Toscana, Italy 189.8
Santa Catarina, Brazil 181.3
Lombardia, Italy 179.1
Dundee, Scottland 166.0
Basque (Alava, Spain) 160.0
Greece 150.1
Italy 141.5
Switzerland 137.8
Ibiza Island, Balearic Archipelago 134.2
Caucasian 116.5
Caucasian 114.2
Dusseldorf, Germany 113.3
Greece 110.7
Marche, Italy 109.0

The High Res World came back as:

Mediterranean 98.67
Northwest European 63.64
Asia Minor 56.06
Arabian 23.58
Eastern European 10.41
India 9.52
Mestizo 8.56
North India 0.66
Finno-Ugrian 0.23
India Tribal .06
Mongolian 0.05
Australian 0.03
North African 0.01

Thanks for any advice anyone has regarding how to interpret this,

Kelly

[Noaide]

STRUCTURE works

I finally managed to import genotype data from asians, caucasians and african americans into STRUCTURE and put it into a triangle plot, allmost all individuals placed themself nicely in each of the respective corners. This happend even after I had to round all alleles numbers to integers because the program dont accept real numbers for loci data.

Cluster 1: Caucasians
Cluster 2: African Americans
Cluster 3: Asians

Now I have to figure out how to get individual results compared to this and how to import frequency data.

Noaide

[Maria_W]

3.0

Any clue as to when the 3.0 version by AncestrybyDNA will be comming out? And will any of you retest with it? I know haplogroupc took his twice and came up with basically the same results. 59% and 61% Native American and settled for 60%. Maria

[Maria_W]

Wow.

Noaide.

That is so cool! How did you do that and how can we use it?

Maria

[Noaide]

Now I have to figure out how to get individual results compared to this and how to import frequency data.

I defined myself as a population and I got admixture estimates for myself. The result seems more realistic than my earlier DNATribes and Omnipop result, if the program could understand decimal alleles the populations would discrimante even better. The program use much time to crunch the numbers using advanced algorythms.

Noaide

[Noaide]

That is so cool! How did you do that and how can we use it?

You need to be computer literate to manage to run this yourself, but when first figuring how to do it, it seem simple to me. However so far I only have raw genotype data for tree populations all living in America and probably admixted to some degree. I need to solve the problem with decimal alleles and import of frequency data.

Noaide

[tomcat]

Well Tom,
If you can't figure out how to use these, then there's not much hope for me as I'm sort of a "Plug and Play" with the allele values type ....

Little hope on that front. I would like to get my computer-wiz sisters into this stuff, but they, like I, are 'older' and otherwise occupied. The best bet would a computer-wiz niece or nephew.

The topic of succession deserves a thread. Who takes over the family history project when we get 'tired'? Who monitors the Mitosearch and Ysearch pages? Who is the contact person for the Surname or Geographic project? Does it all go back to dust?

[Maria_W]

Good idea.

Tom.

Good idea. I'll jump over there.

Maria

[tomcat]

Copy from another thread

You can research your alleles in combination. Each combination is a partial profile. Because every combination has a mirror or opposite combination this allows you to model and test partial profiles for your two parents. It is an experiment to see if one can attribute alleles and allelic combinations to one parent or another.

It is simple to work with three markers at a time as there are only eight combinations or four pairs.

Marker1 A B
Marker2 A B
Marker3 A B

The first combos are columns, all A alleles at each locus and the opposite of all B alleles at each locus.
The second combo is is a zigzag, Marker1 A, Marker2 B, Marker3 A, and the opposite of M1 B, M2 A, M3 B.
The third combo is a combo of the first two, M1 A, M2 A, M3 B and the opposite M1 B, M2 B, MD3 A.
As is the fourth combo of M1 A, M2 B, M3 B and the opposite M1 B, M2 A, M3 A.

You can enter single alleles in Omnipop. But if you enter single alleles on ENFSI it will make them homozygotes. You can use any three markers and try as many combinations of markers as you care to. If you can figure-out how to use four markers let me know.

[Jodee]

Tomcat - well its well worth the experiment - i'm off to zig and zag -

and

Noide, what can i say - your program in the works sounds wonderful -

Thanks to you both for your suggestions and super help.


In light of keeping the "succession" going Tom, i've been thinking of it too, but on a littler scale. It occurred to me the other day when my daughter said i'll just wait for your results, that thats not what its all about - it doesn't stop at me! So i'm hoping when i get to be a grandmother's age that i have instilled enough curiosity in each family member to be tested, rather than having quenched it.

i've been working on a short family "dna" book for cousins and intermediate family with cousin contact info (not that i know many - we're seemingly small) but got in there my dna projects, results, project contact info, as well as some simple charts and visual tools entwined with my family tree - like highlighted mtdna line, my str-x gr-grandparents, etc. Also cd with family tree, oldest pics and records. Theres a page letting them know there are other surname and geographical projects ready for the making, what tests are out there, etc, hoping to inspire that continuous "upkeep". Not on any grand scale mind, but hoping to wake up the sleeping dragon a bit - don't know what i'll wake up, but maybe it will keep some of my efforts alive and even more so, maybe it'll be as exciting to them as it is to me, sigh......... just in case i get "tired"

Jodee