Announcement

Collapse
No announcement yet.

MTHFR

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • prairielad
    replied
    Originally posted by Nikolaa91 View Post
    What test should I purchase in order to get those SNPs tested?
    I can not guarantee snps will be tested which are used to "predict" MTHFR, but the snps I Mentioned above are tested on ftdna's new GSA chip. IT will be the family finder test. Only if one has tested since Ftdna started using new chip version in the last month or so. FTDNA will not give health info, not authorized, but some health snps maybe in raw data file unless they decide to remove the health snps as they claimed with previous versions of raw data files.
    Last edited by prairielad; 1 June 2019, 08:59 PM.

    Leave a comment:


  • Nikolaa91
    replied
    What test should I purchase in order to get those SNPs tested?

    Leave a comment:


  • prairielad
    replied
    according to the following
    Code:
    https://www.xcode.life/23andme-raw-data/mthfr-test-interpret-23andme-mthfr-results/
    In New Family Finder Results look up rs1801133 and rs1801131 and look at their values

    FamilytreeDNA's new GSA chip test both the above SNPs, not sure about earlier chip versions
    New chip also has a SNP listed as MTHFR_c.474A>T_R, chr 1, position 11861219 (not sure how this one can be interpreted)

    Leave a comment:


  • KATM
    replied
    I see. If it's that important to you, it's better to save your money toward the MTHFR testing alone than to wait for FTDNA to change their policy, which realistically may never happen. Also, you may want to read the 23andMe blog post about MTHFR.

    If you really wish to get ancestry information as well, again, save your money and wait for a sale. FTDNA has sales around Christmas, and also has offered coupons in the past to enhance the savings (not guaranteed that they will continue to offer coupons). There are many times throughout the year when FTDNA also offers sales, as well as other companies which might be sold in your country.
    Last edited by KATM; 4 May 2019, 07:59 AM. Reason: added link

    Leave a comment:


  • Nikolaa91
    replied
    I mean I'll have to wait for FTDNA to overcome this, since 23andme isn't delivering testing kits to my country.

    MTHFR testing alone is about 100e in my country, but I would like to get ancestry information as well.

    Leave a comment:


  • KATM
    replied
    Originally posted by Nikolaa91 View Post
    Well ok, I guess I'll have to wait then.
    Do you mean you have to wait to test at 23andMe? 23andMe is the only company that emphasizes providing health results at this time. FTDNA is not seeking the FDA's permission for providing health results, so you would be waiting in vain for health results from them. Neither Ancestry nor MyHeritage provide health results, either.

    Leave a comment:


  • Nikolaa91
    replied
    Well ok, I guess I'll have to wait then.

    Leave a comment:


  • Jim Barrett
    replied
    They did, until they got approval from FDA.

    Leave a comment:


  • Nikolaa91
    replied
    How doesn't 23andme have problem with this?

    Leave a comment:


  • bartarl260
    replied
    Only thing to add is it isn't just the FDA with their fingers in this stuff. California and New York love to stick their regulatory fingers into anything medical that comes into their jurisdiction as well. They're not alone in the practice, they're just the most stringent/shameless about doing it.

    Leave a comment:


  • Nikolaa91
    replied
    Has something changed about this?
    I wanted get DNA test from FTDNA in order find possible MTHFR disorders, I was really disappointed when I saw this topic.

    Leave a comment:


  • Aniara
    replied
    So I tried running Promethease and the results showed absolutely nothing. Working as intended, I suppose. I think their claims are disingenuous, but it is what it is.

    Leave a comment:


  • ltd-jean-pull
    replied
    It's a medicolegal can of worms.

    You need to consider any life or health insurance implications of testing. Explaining this sort of thing is part of genetic counselling. People often think "I don't need counselling - I can handle the truth" but it's not "touchy feely" counselling. Same with testing for HIV for example.

    If you find out you have a genetic mutation that can have health implications and then don't declare it when you apply for insurance that could be considered fraud, and your insurance could be void.

    Sometimes you can work it out if you know someone in your family has a gene and where that gene is. For example if you have nieces and nephews with the "Celtic" haemochromatosis (a recessive condition, although some carriers can have symptoms) and they match you at the loci where this gene is, then you (unless their mother's gene was a spontaneous mutation) would have the gene too.

    Leave a comment:


  • MMaddi
    replied
    Originally posted by Aniara View Post
    Wow,*I don't see why they would want to get in the way of people having that information.
    The FDA's position is that merely giving someone a test result for a SNP, without an explanation by a physician, may lead someone to take the wrong medical action. That does seem a little overbearing, but I think it's worth considering. If someone has a concern about a serious medical condition, I think they need to get advice from a medical professional.

    Leave a comment:


  • Aniara
    replied
    Wow,*I don't see why they would want to get in the way of people having that information.

    Leave a comment:

Working...
X