R1b SNP sale

[haleaton]

What is definition and tree location of BY2895 & BY2896?

FTDNA has sale on at 79$ for R1b SNP pack.

Includes 61 SNPs on the Haplotree:

M343, L278, P297, M269, L23, L51, P310, P311, P312, L21, DF21, M222, Z255, Z253, L513, L371, CTS3386, CTS4466, CTS1751, Z195, SRY2627, Z295, U152, L2, Z49, Z367, PF6610, CTS5689, Z36, Z225, DF19, CTS11567, F2691, CTS10429, U106, Z381, L48, Z9, L47, Z156, Z18, CTS4528, PF6714, PF7589, PF3252, CTS7763, Z1862, CTS6937, F2863, M73, V88, L238, DF99, L389, M335, DF13, DF63, DF95, DF49, S11601, Z17

Includes 79 SNPs not on the Haplotree:

BY2895, A6454, BY2896, A1773, A2150, A274, A4670, A517, BY2823, BY2868, BY575, CTS11994, CTS5330, DF110, DF17, DF41, DF81, DF83, DF88, DF90, FGC10516, FGC11134, FGC13620, FGC13780, FGC20761, FGC22501, FGC396, FGC5301, FGC5336, FGC5338, FGC5344, FGC5345, FGC5351, FGC5354, FGC5356, FGC5367, FGC5373, FGC5494, FGC5798, L1335, L277, L408, L584, L617, L881, M1994, MC14, PF331, PF6658, PF7562, PF7600, S1026, S1051, S11493, S12025, S1567, S16264, S1688, S18632, S18827, S7721, Y5058, Z16500, Z198, Z209, Z2103, Z2106, Z2109, Z251, Z2542, Z2573, Z262, Z296, Z301, Z302, Z56, Z8056, DF103, Z17300

Is there a list of definition of BY SNPs somewhere?

[1798]

Is there a list of definition of BY SNPs somewhere?

Ask Mikewww at anthrogenica about them. He helped FTDNA to set up this SNP pack.

[lgmayka]

I understand that there might be an upgrade to the BigY next year. Any news on this? Since I can't afford the BigY right now, it might be worth waiting for the new version.

The interview (with FTDNA's CEO) I read indicated that he was planning
- IT improvements later this year
- A somewhat lower price next year.

Please understand that a "somewhat" lower price might simply be a regularization of the usual discount/coupon price ($488.75 right now with the cjs2015 coupon code).

[lgmayka]

As I posted earlier in this thread, anyone who's already in a haplogroup project (other than the R1b Gateway Project) will get little or, more likely, no benefit from this backbone panel. They're essentially wasting their money.
...
Otherwise, they should check with the administrators of their haplogroup project if there is a more downstream SNP panel available that's appropriate for them or when one will be available.

If a specific R1b clade already has a SNP pack, or is definitely working on one with FTDNA, then certainly members of that subclade should wait for it. My understanding is that this is true of U106, for example.

But if a clade has no SNP pack of its own now or on the horizon, this "backbone" SNP pack may well be worth its $79 introductory price. According to project administrators on another forum, this is indeed the case for the U152 and DF27 clades.

For example:
- In an earlier Deep Clade test, many people tested L2+ L20- . (L2 is a subclade of U152.) This new SNP pack will test Z49, Z367, and many more subclades of L2.
- Some people have tested (only) DF27+ Z196- . This new SNP pack will test many more subclades of DF27 (though not, ironically, DF27 itself).

[jbarry6899]

This new SNP pack will test many more subclades of DF27 (though not, ironically, DF27 itself).

The following was posted on Anthrogenica regarding DF27:

". . . the technology used prohibits testing DF27 due to where it is situated. These SNP packs do not use oglionucleotides and PCR (Polymerase Chain Reaction) amplification used by Sanger's primer-extension method. The Sanger method is capable of sequencing contiguous sub-regions on both complimentary strands where the variant base-pair exists.

Rather, this tech behaves more like the probes used on bead-chip products that can only determine a particular state (ancestral or derived) of a nucleotide base. If a probe that terminates with the ancestral state binds to the sample DNA, the sensor detects the ancestral state. If a probe that terminate with the expected derived state binds to the sample DNA, the sensor detects the derived state. It does not matter whether the probe binds to the forward or reverse strand. As with bead-chips, it is unknowable if a probe erroneously binds to the wrong position. It is also unknowable if manufacturing flaws resulted in bad probes that fail to bind to any target.

DF27 is situated in a position on the Y-chromosome that requires dual sets of primers to isolate and amplify the desired target via the Sanger method. That isolation stage is not possible with genotyping chips nor the the tech that FTDNA uses for these SNP packs."

Jim

[lgmayka]

Here are forum posts endorsing the new SNP pack for:
U152
U152 > L2 - 16 out of 18 subclades covered
DF27 - All subclades covered except the ancient, mysterious, rare BY653

[haleaton]

Here are forum posts endorsing the new SNP pack for:
U152
U152 > L2 - 16 out of 18 subclades covered
DF27 - All subclades covered except the ancient, mysterious, rare BY653

There is a possibility that BY2895 & BY2896 are the other two known L2 branches, whose SNPs had not been given names, but were in Big Y. Keep my fingers crossed for 18/18.

[gtc]

If you're confirmed U106, then wait!

The following quote is from Charles Moore, U106 Project administrator and ISOGG R1b-U106 and Subclades administrator:

One more time (undoubtedly to be repeated ad infinitum), NOBODY who has tested U106+, OR BELOW, can derive any benefit from the R1b "Backbone" panel. This is a great test, but its SOLE purpose is to determine what branch of R1b you belong to. If you already know what branch of R1b you belong to, this test is COMPLETELY USELESS.

I am meeting with FTDNA next week to give them my advice on how to proceed with derivative U106 SNP Packs. People who are in U106, but will not be taking the much better Big Y or FGC tests, presumably for financial reasons, will be advised by us, HERE, and elsewhere, what derivative SNP Packs to order, once they are available, soon. Stay tuned.

NOBODY IN THE U106 PROJECT SHOULD ORDER THE BACKBONE TEST. NOBODY!!!

[1798]

The U106 pack will benefit some of those who are U106 but not all. There is no pack that can resolve my line. It will take a Big Y. It would be better if the Big Y came down in price.

This R1b backbone test is a great offer for any R1b predicted from their Ydna12,Ydna25,Ydna37 and Ydna 67 tests.

[LarryBurford]

The U106 pack will benefit some of those who are U106 but not all. There is no pack that can resolve my line. It will take a Big Y. It would be better if the Big Y came down in price.

This R1b backbone test is a great offer for any R1b predicted from their Ydna12,Ydna25,Ydna37 and Ydna 67 tests.

I ordered the pack for my dad who is tested at Y67. I am planning on ordering my son an myself a Y12 or Y25 kit just so we have a Y DNA on file. When I get a confirmed haplogroup for my dad Can't I just order the SNP test for that particular SNP for my son and myself to give us our confirmed Haplogroup since it will be the same as my dads for both of us?

[K. L. Adams]

I ordered the pack for my dad who is tested at Y67. I am planning on ordering my son an myself a Y12 or Y25 kit just so we have a Y DNA on file. When I get a confirmed haplogroup for my dad Can't I just order the SNP test for that particular SNP for my son and myself to give us our confirmed Haplogroup since it will be the same as my dads for both of us?

Yep! You can just order the specific SNP for $39.

[1798]

I ordered the pack for my dad who is tested at Y67. I am planning on ordering my son an myself a Y12 or Y25 kit just so we have a Y DNA on file. When I get a confirmed haplogroup for my dad Can't I just order the SNP test for that particular SNP for my son and myself to give us our confirmed Haplogroup since it will be the same as my dads for both of us?

There is no need to order a YDNA test or SNP test for yourself or your son. Your dad's and you and your son's should be the exact same. I wasted money on family members.

[T E Peterman]

The sensible thing is to only order SNPs/ Big Y for one patrilineal member, whose paper connection has been verified by Family Finder.

The earliest MRCA for most FF matches lived between maybe 1780 & 1820.

If several close relatives have already y-str tested & they match, I suggest only upgrading one of them to SNPs/ Big Y.

Timothy Peterman

[1798]

The sensible thing is to only order SNPs/ Big Y for one patrilineal member, whose paper connection has been verified by Family Finder.

The earliest MRCA for most FF matches lived between maybe 1780 & 1820.

If several close relatives have already y-str tested & they match, I suggest only upgrading one of them to SNPs/ Big Y.

Timothy Peterman

I didn't realize when I got dna tested that I was giving up the dna of my family and first cousins, second cousins etc.etc. I certainly heard enough about it from them since!!

[T E Peterman]

No one's DNA exists in isolation. Your y-DNA is inherited from your patriline & shared with all of your patrilineal (usually same surname) relatives.

Bits & pieces of your autosomal DNA are shared with relatives on all sides of your family. That is why Family Finder achieves the mystical task of finding family.

Timothy Peterman