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  #1  
Old 11th February 2014, 01:34 AM
PDHOTLEN PDHOTLEN is offline
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Smile New FMS match (U5b2b2)

I've been notified that I have a new U5b2b2 FMS match. That is my second. This one has a genetic distance of 2, which probably indicates a common ancestor back in the Dark Age. He hasn't given any information about himself (yet?). He is not shown to match me in HVR1 or HVR1+HVR2. That could mean the "2" are in the control region, with the coding region matching me exactly.

Last edited by PDHOTLEN; 11th February 2014 at 01:43 AM.
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Old 14th March 2014, 08:56 PM
PDHOTLEN PDHOTLEN is offline
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Smile

Lo and behold, I now have a third FMS match. This one is like the second, with a distance of 2. It also does not match my HVR1 or HVR2. It would be nice if they would join the U5b project. So I now have one match with a distance of one; and the two most recent matches with a distance of 2. The earliest one matches my HVR1 and HVR2, which means a coding region difference.

Last edited by PDHOTLEN; 14th March 2014 at 09:02 PM.
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Old 15th March 2014, 03:43 AM
1798 1798 is offline
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Quote:
Originally Posted by PDHOTLEN View Post
Lo and behold, I now have a third FMS match. This one is like the second, with a distance of 2. It also does not match my HVR1 or HVR2. It would be nice if they would join the U5b project. So I now have one match with a distance of one; and the two most recent matches with a distance of 2. The earliest one matches my HVR1 and HVR2, which means a coding region difference.
A GD of one is equal to 3700 and two 7400 ybp.
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Old 15th March 2014, 04:27 PM
PDHOTLEN PDHOTLEN is offline
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Originally Posted by 1798 View Post
A GD of one is equal to 3700 and two 7400 ybp.
Thanks for the information. Common ancestor (with GD of 2) back in the Mesolithic, I guess.
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Old 15th March 2014, 04:34 PM
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Rebekah Canada Rebekah Canada is offline
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Hi,

It is not that bad. More like 1,500 years +/- 1,500 years per non-heteroplasmic difference.
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A GD of one is equal to 3700 and two 7400 ybp.
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Old 15th March 2014, 04:35 PM
1798 1798 is offline
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Thanks for the information. Common ancestor (with GD of 2) back in the Mesolithic, I guess.
I think that the general consensus is that MT Eve lived around 200,000 years ago and the average number of MT mutations are 55. My son has 55 and I have 66 so you could divide 200,000 by 55.
Maybe I have it wrong but some other posters may have a better idea.
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Old 15th March 2014, 06:05 PM
GST GST is offline
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A GD of one is equal to 3700 and two 7400 ybp.
One mutation in the full mtDNA genome per 3700 years is a common estimate of the mutation rate, but assuming two people share a maternal ancestor 3700 years ago, and they both have the average of one mutation, then a GD of two would be 3700 years, so Rebekah's estimate seems about right. It is also important to take into account the uncertainty range - some 1 step matches could share a common maternal ancestor more than 1500 years while some could be much more recent than 1500 years. For people who don't have any 0-step matches, I think it is worthwhile contacting the 1 and 2 step matches. In most cases they probably won't share a recent common ancestor, but in some cases they might.
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Old 15th March 2014, 06:15 PM
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Rebekah Canada Rebekah Canada is offline
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Hi,

Yes, they might indeed. Especially if the mutation is on something fast moving like 309.1C.
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...In most cases they probably won't share a recent common ancestor, but in some cases they might.
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Old 17th March 2014, 12:13 AM
PDHOTLEN PDHOTLEN is offline
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I noticed today in looking at one of my rare HVR1+HVR2 matches that, in the list of surnames given, there appears to be 3 that are Native American, including a Cherokee reference. A couple of other surnames may point back to Long Island (early 1700s in my case). This could be cousins who went south during the 1700s with my line.

Last edited by PDHOTLEN; 17th March 2014 at 12:16 AM.
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Old 7th June 2014, 07:12 PM
rainbow rainbow is offline
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PDHotlen, Congratulations!


I haven't received an email notification but I logged in yesterday and found out that I also have FMS matches now, two people who are H1c12 like me, and both are at a genetic distance of 1.





Quote:
Originally Posted by 1798 View Post
A GD of one is equal to 3700 and two 7400 ybp.

Quote:
Originally Posted by Rebekah Canada View Post
More like 1,500 years +/- 1,500 years per non-heteroplasmic difference.


Which one of these is correct?

Last edited by rainbow; 7th June 2014 at 07:20 PM.
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