V5 Chip

[ech124]

Apparently 23andme has just started giving new results based on their customized V5 chip.

My question is has anyone successfully transferred to FTDNA using that file (it has V5 right in the file name)?

I know that for a while FTDNA allowed V3, but not V4. They had to do special programming to allow V4. Now that there is V5, will that be rejected also?

[ech124]

I am hearing some more information about the V5 chip.

It just came into production at 23andme this week. It will take an unknown period of time to replace every machine, but it will happen.

Someone uploaded the new file to Gedmatch, and based on comparing it to a FTDNA file there, there was only about 159000 SNPs in common. Based on that, I think there is no way FTDNA can do anything with a V5 transfer. That will mean a decline in 23andme transfers as their database eventually becomes V5 dominated.

[georgian1950]

I am hearing some more information about the V5 chip.

It just came into production at 23andme this week. It will take an unknown period of time to replace every machine, but it will happen.

Someone uploaded the new file to Gedmatch, and based on comparing it to a FTDNA file there, there was only about 159000 SNPs in common. Based on that, I think there is no way FTDNA can do anything with a V5 transfer. That will mean a decline in 23andme transfers as their database eventually becomes V5 dominated.

That does not bode well for GEDmatch, or quite frankly for autosomal matching in general.

Jack

[georgian1950]

That does not bode well for GEDmatch, or quite frankly for autosomal matching in general.

Jack

Interestingly, GEDmatch has added this on its homepage:

"Aug 10 2017 NOTICE to 23andMe Customers: 23andMe is now using the GSA chip for their new V5 raw DNA file results. This format is not compatible with the regular GEDmatch upload, but can be used with the GEDmatch Genesis upload. Use the link in the lower right column of this page."

[mcornejo]

I tested in 23andme and was not able to import their V5 chip raw results in FTDNA. I went on the new GEDmatch tool, Genesis, where I have imported my FTDNA Family Finder results, uploaded 23andme V5 results, and when comparing to my FTDNA FF kit, the "Overlap" field returns a value of 159,751, whilst when comparing my FTDNA FF kit to my parents', the "Overlap" value is higher up to 680,568. "Overlap" is defined by GEDmatch as the number of positions that exist in common between both kits, without regard to whether they match or not.

Doing a quick visual inspection, I can notice that for other 23andme kits, the Overlap is higher in excess of 300,000, perhaps pre V5 kits, and for Ancestry.com in excess of 400,000.

[oleg.meier]

I've just converted V5 to V4 with

https://github.com/2sh/vcf-to-23andme

First converted to genome.db than back to 23andme. upload successfull

[prairielad]

I've just converted V5 to V4 with

https://github.com/2sh/vcf-to-23andme

First converted to genome.db than back to 23andme. upload successfull

Believe above imputes values, personally I think it would be just be better to spend the $79 for Family Finder and receive the actual tested and verified SNPs) vs imputed ones (up to 540000 imputed SNPS)

https://dna-explained.com/2017/10/04...ng-comparison/