Go Back   Family Tree DNA Forums > General Interest > Scientific Papers

Scientific Papers For talk of scientific papers on population genetics, archaeology, and anthropology related to DNA and personal ancestry testing.

Reply
 
Thread Tools Display Modes
  #1  
Old 31st May 2015, 01:20 AM
PNGarrison PNGarrison is offline
H4a1a4a | R1-BY3322
 
Join Date: Dec 2013
Posts: 412
Genome-wide signatures of male-mediated migration shaping the Indian gene pool.

http://www.ncbi.nlm.nih.gov/pubmed/25994871
not open access

J Hum Genet. 2015 May 21. doi: 10.1038/jhg.2015.51. [Epub ahead of print]
Genome-wide signatures of male-mediated migration shaping the Indian gene pool.
ArunKumar G1, Tatarinova TV2, Duty J3, Rollo D3, Syama A4, Arun VS4, Kavitha VJ5, Triska P6, Greenspan B3, Wells RS7, Pitchappan R8; Genographic Consortium.

Abstract
Multiple questions relating to contributions of cultural and demographical factors in the process of human geographical dispersal remain largely unanswered. India, a land of early human settlement and the resulting diversity is a good place to look for some of the answers. In this study, we explored the genetic structure of India using a diverse panel of 78 males genotyped using the GenoChip. Their genome-wide single-nucleotide polymorphism (SNP) diversity was examined in the context of various covariates that influence Indian gene pool. Admixture analysis of genome-wide SNP data showed high proportion of the Southwest Asian component in all of the Indian samples. Hierarchical clustering based on admixture proportions revealed seven distinct clusters correlating to geographical and linguistic affiliations. Convex hull overlay of Y-chromosomal haplogroups on the genome-wide SNP principal component analysis brought out distinct non-overlapping polygons of F*-M89, H*-M69, L1-M27, O2a-M95 and O3a3c1-M117, suggesting a male-mediated migration and expansion of the Indian gene pool. Lack of similar correlation with mitochondrial DNA clades indicated a shared genetic ancestry of females. We suggest that ancient male-mediated migratory events and settlement in various regional niches led to the present day scenario and peopling of India.Journal of Human Genetics advance online publication, 21 May 2015; doi:10.1038/jhg.2015.51.
Reply With Quote
  #2  
Old 4th June 2015, 08:04 PM
MerryB MerryB is offline
FTDNA Customer
 
Join Date: Jan 2012
Posts: 147
I'm stupid. "Male-mediated" means what, in this context, please?
Reply With Quote
Reply

Bookmarks


Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 
Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Genome-wide ancestry of 17th-century enslaved Africans from the Caribbean PNGarrison Scientific Papers 20 19th May 2015 08:44 PM
Genome-wide insights into the genetic history of human populations PNGarrison Scientific Papers 0 3rd April 2015 08:09 AM
A genome-wide study of modern-day Tuscans: revisiting Herodotus's theory on the origi PNGarrison Scientific Papers 0 16th December 2014 07:00 AM
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of PNGarrison Scientific Papers 4 12th December 2014 11:23 PM
96.66% Western European (Orcadian), 2,83% Southeast Indian, North Indian (?) PeterLarsen myOrigins Basics 9 16th March 2014 01:16 PM


All times are GMT -5. The time now is 07:18 AM.


Family Tree DNA - World Headquarters

1445 North Loop West, Suite 820
Houston, Texas 77008, USA

Phone: (713) 868-1438 | Fax: (832) 201-7147
Copyright 2001-2010 Genealogy by Genetics, Ltd.
Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2018, Jelsoft Enterprises Ltd.