*The Current State of L21 (07 August 2012): The discovery of the SNP DF13 has split L21 into a very large DF13+ group and a thus far much smaller DF13- group. All of the known L21 subclades except DF63 are DF13+, meaning they are downstream of DF13, as well as L21.
If you are L21+ and have not yet tested positive for one of the L21 subclades, you should test for DF13. If you get a DF13+ result, then you can focus on testing for the known DF13+ subclades: DF23, L513, L96, L144, Z255, Z253, DF21, L371, and DF41. DF49 is thought to be between DF13 and DF23, but that has not been confirmed yet. If you get a positive result for one of those subclades, then you can focus on the branches of those subclades. If you have already tested positive for one of the DF13 subclades, you do not need to test for DF13.
If you get a DF13- result, you should test for DF63. Thus far, it is the only known subclade of L21 that is DF13-.
It is possible to be both DF13- and DF63-, however. We have a few men in that category already.
If you are L21+ and have not yet tested positive for one of the L21 subclades, you should test for DF13. If you get a DF13+ result, then you can focus on testing for the known DF13+ subclades: DF23, L513, L96, L144, Z255, Z253, DF21, L371, and DF41. DF49 is thought to be between DF13 and DF23, but that has not been confirmed yet. If you get a positive result for one of those subclades, then you can focus on the branches of those subclades. If you have already tested positive for one of the DF13 subclades, you do not need to test for DF13.
If you get a DF13- result, you should test for DF63. Thus far, it is the only known subclade of L21 that is DF13-.
It is possible to be both DF13- and DF63-, however. We have a few men in that category already.
Comment