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  #21  
Old 23rd November 2015, 04:53 PM
DWFlineage DWFlineage is offline
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I think you are onto something

Quote:
Originally Posted by Alexander View Post
Dear Ann and Douglas!

Now I'm waiting for the results from expert, and I noticed that V20 is the daughter of V-C16298T!. What does the symbol ! mean? What is time distance between the two groups, maybe 3000 years. Maybe V26 is the sister of V20?

The V-C16298T! are concentrated near Scotland! So the scenario of it's transfer to Russian seems for me exciting. Now I'm thinking how could it happen.

With respect,
Alexander
Alexander,

I think you are onto something in regards to V26 & your V20 both having C16298T mutation. Let me know what the experts have to say.

Respectfully, Doug
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  #22  
Old 25th November 2015, 07:12 AM
Ann Turner Ann Turner is offline
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Quote:
Originally Posted by Alexander View Post
Dear Ann and Douglas!

Now I'm waiting for the results from expert, and I noticed that V20 is the daughter of V-C16298T!. What does the symbol ! mean? What is time distance between the two groups, maybe 3000 years. Maybe V26 is the sister of V20?

The V-C16298T! are concentrated near Scotland! So the scenario of it's transfer to Russian seems for me exciting. Now I'm thinking how could it happen.

With respect,
Alexander
This gets kind of complicated. The ! means a reverse mutation. The CRS has a T at position 16298. Haplogroup V is defined by a C at that location. But as time went on, some branches of haplogroup V had a mutation at the very same location, so they have a T again. That means that 16298 won't show up on a list of differences from the CRS.

The age of a haplogroup is estimated by looking at the amount of variation that has accumulated since the clan mother started the branch. There aren't enough full mitochondrial sequences to have much confidence in the age, but FWIW, Behar gives these dates

V 9700 years
V19 2900 years
V20 5000 years
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  #23  
Old 25th November 2015, 12:01 PM
DWFlineage DWFlineage is offline
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Thanks for that info

Quote:
Originally Posted by Ann Turner View Post
This gets kind of complicated. The ! means a reverse mutation. The CRS has a T at position 16298. Haplogroup V is defined by a C at that location. But as time went on, some branches of haplogroup V had a mutation at the very same location, so they have a T again. That means that 16298 won't show up on a list of differences from the CRS.

The age of a haplogroup is estimated by looking at the amount of variation that has accumulated since the clan mother started the branch. There aren't enough full mitochondrial sequences to have much confidence in the age, but FWIW, Behar gives these dates

V 9700 years
V19 2900 years
V20 5000 years
Ann,

Nice to know at least an estimate of V19 haplogroup. I have not found any research on the geography of V19. If you come across some geography info on V19, I would be interested.

Best regards, Doug
Kit#122883
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  #24  
Old 9th December 2015, 04:41 PM
Alexander Alexander is offline
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New Data

Dear Ann and Douglas,

finally I obtained data from experts, so I can display it. I was classified as V20 descender according to these mutations

R0 G73A, A11720G
HV T14767C
HV0 T72C, T16300C
HV0a C15905T
V G4581A
V20 G8585A, C16258T

is it real v20? I see that it slightly differ from classic markers, for example the last step is desscribed in both RSRS and RCRS as 8584 16256

some other defining mutation position numbers slightly differ from classical

What does it mean?

Thanks a lot for possible help

With respect,
Alexander
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  #25  
Old 9th December 2015, 05:33 PM
DWFlineage DWFlineage is offline
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Join Date: Feb 2014
Posts: 199
Greetings

Quote:
Originally Posted by Alexander View Post
Dear Ann and Douglas,

finally I obtained data from experts, so I can display it. I was classified as V20 descender according to these mutations

R0 G73A, A11720G
HV T14767C
HV0 T72C, T16300C
HV0a C15905T
V G4581A
V20 G8585A, C16258T

is it real v20? I see that it slightly differ from classic markers, for example the last step is desscribed in both RSRS and RCRS as 8584 16256

some other defining mutation position numbers slightly differ from classical

What does it mean?

Thanks a lot for possible help

With respect,
Alexander
Alexander,

Glad that the experts got back to you. I learned something about my V19 group from Ann, that it is estimated 2700 years old. I believe Ann stated your V20 group is 5000 years back. Maybe Ann can give you more information. I had also thought that each haplogroup branched off from the previous one, but Ann explained its a "red herring", so I am still learning. I know that admin separated me from V19 folks by labeling me as V19a, because of my two heteroplasmies, but that is just for admin purposes. I would be interested to know how our two haplogroups are connected?

Best regards, Doug

Kit#122883
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  #26  
Old 10th December 2015, 10:54 AM
Ann Turner Ann Turner is offline
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Join Date: Apr 2003
Posts: 1,084
Quote:
Originally Posted by Alexander View Post
Dear Ann and Douglas,

finally I obtained data from experts, so I can display it. I was classified as V20 descender according to these mutations

R0 G73A, A11720G
HV T14767C
HV0 T72C, T16300C
HV0a C15905T
V G4581A
V20 G8585A, C16258T

is it real v20? I see that it slightly differ from classic markers, for example the last step is desscribed in both RSRS and RCRS as 8584 16256

some other defining mutation position numbers slightly differ from classical

What does it mean?

Thanks a lot for possible help

With respect,
Alexander
This is still a bit different than the conventions used by the genetic genealogy companies. One reason for the offset could be that you have an insertion compared to the CRS. There's one very common one, 315.1C (where the CRS has a rare version). If your source just keeps on counting bases, that would move the position of subsequent markers. There's also a convention to skip over an error that introduced a new base in the original CRS sequence at about 3107 (from memory). Technically, the genetic genealogy companies compare your results to the rCRS (revised CRS).

All these insertions and deletions make it hard to do a one-to-one comparison of your numbers. Could your source give you a FASTA file? That lists your sequence base by base, and you can run the FASTA file with James Lick's utility to see how things would be numbered.

http://dna.jameslick.com/mthap/
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