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Forum: mtDNA - Advanced Topics 8th December 2017, 06:28 PM
Replies: 9
Views: 970
Posted By GST
It appears that the RSRS is always the reference...

It appears that the RSRS is always the reference used for the genetic distance, not the reference value of the marker for the haplogroup. I listed two examples below for hapgroup H10 for which 16093...
Forum: mtDNA - Advanced Topics 8th December 2017, 12:29 PM
Replies: 9
Views: 970
Posted By GST
Yes, in your FTDNA full sequence match list the...

Yes, in your FTDNA full sequence match list the heteroplasmy counts as 1 step in the genetic distance. Heteroplasmies are more common at some markers than others, and I generally ignore common...
Forum: mtDNA - Advanced Topics 8th December 2017, 12:01 PM
Replies: 3
Views: 167
Posted By GST
You can upload your 23andMe mtDNA results to...

You can upload your 23andMe mtDNA results to James Lick's mthap web tool. This will give you a list of the SNPs relative to the rCRS or RSRS reference sequences which you can then compare your FTDNA...
Forum: mtDNA - Genealogy Basics 5th November 2017, 11:36 AM
Replies: 32
Views: 2,535
Posted By GST
Back mutations do occur in mtDNA but they are...

Back mutations do occur in mtDNA but they are relatively infrequent compared to the total set of mutations that define a haplogroup, and when you test the full sequence different subclades will not...
Forum: mtDNA - Genealogy Basics 5th November 2017, 01:33 AM
Replies: 32
Views: 2,535
Posted By GST
Here is another way to look at the results, for...

Here is another way to look at the results, for my subclade U5a2a1 which is estimated to be about 6000 years old, there are 185 full sequence samples in the U5 project and in GenBank. On average...
Forum: mtDNA - Genealogy Basics 5th November 2017, 01:56 AM
Replies: 32
Views: 2,535
Posted By GST
For the mutation rate, the 2009 Soares et al....

For the mutation rate, the 2009 Soares et al. paper "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". Here is the key text: "The substitution rate for the entire...
Forum: mtDNA - Genealogy Basics 4th November 2017, 01:58 PM
Replies: 32
Views: 2,535
Posted By GST
The number of generations in the chart are wrong...

The number of generations in the chart are wrong by about a factor of 10. That is a very poor approximation. But the real problem is that, because of the large variability in the accumulation of new...
Forum: mtDNA - Genealogy Basics 1st November 2017, 11:39 PM
Replies: 32
Views: 2,535
Posted By GST
The genetic distance chart is not accurate - on...

The genetic distance chart is not accurate - on average, the number of generations should be increased by about a factor of 10, but average genetic distances are not very meaningful for evaluating...
Forum: mtDNA - Haplogroup & Origins Basics 1st October 2017, 12:43 PM
Replies: 12
Views: 1,577
Posted By GST
It is also possible that your T1a1 lineage...

It is also possible that your T1a1 lineage originated in the Middle East and was part of the early Jewish Diaspora. The lack of additional recent mtDNA mutations makes it impossible to determine the...
Forum: mtDNA - Haplogroup & Origins Basics 1st October 2017, 12:27 PM
Replies: 12
Views: 1,577
Posted By GST
The average mtDNA mutation rate is closer to one...

The average mtDNA mutation rate is closer to one in 3000 years, but there is extremely large variability in the number of mutations that accumulate in individual lineages. Some lineages can...
Forum: mtDNA - Genealogy Basics 29th September 2017, 11:30 AM
Replies: 8
Views: 972
Posted By GST
Have you joined the X Haplogroup project...

Have you joined the X Haplogroup project (https://www.familytreedna.com/groups/x/about/results)? If you share your mtDNA coding region results with the project admin, they might be able to help...
Forum: mtDNA - Advanced Topics 17th August 2017, 11:25 AM
Replies: 1
Views: 934
Posted By GST
It is possible that you are in a new, as yet...

It is possible that you are in a new, as yet unnamed subclade of B2. You can compare your results to other B2 samples in the research data base GenBank. Ian Logan list these samples at this link:...
Forum: mtDNA - Genealogy Basics 3rd June 2017, 07:58 PM
Replies: 5
Views: 1,583
Posted By GST
Ignore the FTDNA chart that predicts generations...

Ignore the FTDNA chart that predicts generations for mtDNA matches, it is wildly inaccurate. FTDNA needs to replace the chart with a much more nuanced description of how to interpret mtDNA matches. ...
Forum: mtDNA - Genealogy Basics 22nd April 2017, 05:30 PM
Replies: 24
Views: 3,603
Posted By GST
U2d is estimated to be about 23,000 years old, is...

U2d is estimated to be about 23,000 years old, is relatively rare, and is found mostly from the Middle East to Europe. If you join the FTDNA U2 project and share your coding region results with the...
Forum: mtDNA - Genealogy Basics 15th April 2017, 06:29 PM
Replies: 2
Views: 854
Posted By GST
There is not a simple answer to this question -...

There is not a simple answer to this question - first you should check to see which mutations are being counted as part of the GD 3, and if common mutations or heteroplasmies are being counted, you...
Forum: mtDNA - Haplogroup & Origins Basics 12th March 2017, 07:14 PM
Replies: 58
Views: 4,784
Posted By GST
Yes, you should test the mtDNA full sequence. It...

Yes, you should test the mtDNA full sequence. It is possible that your L2a subclade has been in the Middle East for many thousands of years, but you need to know the specific subclade to say anything...
Forum: mtDNA - Advanced Topics 10th March 2017, 11:22 AM
Replies: 3
Views: 1,690
Posted By GST
Yes - in general, these are the most volatile of...

Yes - in general, these are the most volatile of the hyper variable region (HVR) markers. But other markers can also be very volatile, for example, in some haplogroups 16093 seems to be much less...
Forum: mtDNA - Haplogroup & Origins Basics 10th March 2017, 11:09 AM
Replies: 58
Views: 4,784
Posted By GST
Reposting my response to the other thread: L2a...

Reposting my response to the other thread: L2a is estimated to share a common maternal ancestor about 80,000 years ago, so you could be extremely distantly related to most of your matches. You...
Forum: mtDNA - Advanced Topics 7th March 2017, 04:29 PM
Replies: 1
Views: 877
Posted By GST
L2a is estimated to share a common maternal...

L2a is estimated to share a common maternal ancestor about 80,000 years ago, so you could be extremely distantly related to most of your matches. You should look at your closest matches and try to...
Forum: mtDNA - Advanced Topics 6th March 2017, 02:41 PM
Replies: 3
Views: 1,690
Posted By GST
Yes, you interpreted this correctly. However, I...

Yes, you interpreted this correctly. However, I don't think it is useful to include highly volatile markers like 152, 195, 16362, etc as unnamed branch point in the phylotree. There will be some...
Forum: mtDNA - Genealogy Basics 17th February 2017, 04:46 PM
Replies: 2
Views: 1,096
Posted By GST
This is one of the more common mutations, and,...

This is one of the more common mutations, and, because of the possibility of parallel mutations and reverse mutations, it is less reliable for constructing phylogenetic trees. It could still be...
Forum: mtDNA - Advanced Topics 15th February 2017, 12:26 AM
Replies: 6
Views: 2,284
Posted By GST
While most people have some matches, there are...

While most people have some matches, there are many people who have no matches at any level, especially for members of rare haplgroups. You can check Ian Logan's page to see if any of the L3f1b4a1...
Forum: mtDNA - Haplogroup & Origins Basics 17th January 2017, 11:26 PM
Replies: 16
Views: 4,180
Posted By GST
The FTDNA mtDNA FAQ has a detailed explanation of...

The FTDNA mtDNA FAQ has a detailed explanation of heteroplasmies, and there are a few other hot spots that could be ignored. From Phylotree: "The mutations 309.1C(C), 315.1C, AC indels at 515-522,...
Forum: mtDNA - Genealogy Basics 17th January 2017, 11:20 PM
Replies: 1
Views: 1,017
Posted By GST
I volunteer for several of the U and H haplogroup...

I volunteer for several of the U and H haplogroup projects but I don't have any special expertise in haplogroup V, so I would recommend joining the V project, and hopefully there is an active...
Forum: mtDNA - Haplogroup & Origins Basics 15th January 2017, 10:13 PM
Replies: 16
Views: 4,180
Posted By GST
Yes, but you should ignore some of these that are...

Yes, but you should ignore some of these that are extremely common and are not significant, including 309.1C, 315.1C, 522.1A, 522.2C, C16519T. FTDNA excludes 309 and 315 when evaluating the GD, but...
Showing results 1 to 25 of 500

 
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