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Forum: mtDNA - Advanced Topics 4th April 2018, 09:38 PM
Replies: 7
Views: 3,177
Posted By GST
I still need to update the U5 project results...

I still need to update the U5 project results summary page - need a really long snow storm and being snowed in for several days to focus on this - we now have 22 U5a2e samples, mostly located roughly...
Forum: mtDNA - Haplogroup & Origins Basics 24th March 2018, 05:01 PM
Replies: 4
Views: 1,181
Posted By GST
There is no benefit to testing your mother, her...

There is no benefit to testing your mother, her results will very likely be identical to yours. Multiple non-identical samples are needed to add a new subclade to the mtDNA tree, so multiple samples...
Forum: Group Administrators - Advanced Chat 24th March 2018, 10:55 AM
Replies: 6
Views: 675
Posted By GST
I'm getting more new project members who only...

I'm getting more new project members who only tested the mtDNAplus/HVR region and yet have a very specific subclade prediction as if they had tested the full mtDNA sequence. Is it possible that...
Forum: Group Administrators - Advanced Chat 28th February 2018, 08:39 PM
Replies: 6
Views: 675
Posted By GST
That is normal. Typically FTDNA will only assign...

That is normal. Typically FTDNA will only assign the highest level haplogroup name based on HVR results, and the FMS test is needed to get the more specific subclade. However, I have seen two recent...
Forum: mtDNA - Haplogroup & Origins Basics 27th February 2018, 09:41 PM
Replies: 2
Views: 253
Posted By GST
Yes, you should test the full mtDNA sequence. If...

Yes, you should test the full mtDNA sequence. If you are R7, the full sequence will identify a more specific subclade. You can see the R7 results that have been published in the research data base...
Forum: Group Administrators - Advanced Chat 27th February 2018, 09:35 PM
Replies: 6
Views: 675
Posted By GST
Yes, absolutely certain. Did FTDNA specifically...

Yes, absolutely certain. Did FTDNA specifically identify you as K1a10a or did you determine this based on your HVR results?
Forum: Group Administrators - Advanced Chat 27th February 2018, 02:28 PM
Replies: 6
Views: 675
Posted By GST
mtDNAPlus/HVR tests with specific subclade assignments?

I've seen two mtDNA project members who only tested mtDNAplus for the HVR region but they received very specific subclade assignments, as would be expected if they had tested the full mtDNA sequence....
Forum: Group Administrators - Advanced Chat 27th January 2018, 08:55 AM
Replies: 5
Views: 611
Posted By GST
Darren - I'm seeing more errors in new mtDNA...

Darren - I'm seeing more errors in new mtDNA haplogroup assignments. Is there a way I can report these directly to the IT staff or should I PM you for each one?

thanks,
Gail
Forum: mtDNA - Advanced Topics 25th January 2018, 09:15 PM
Replies: 3
Views: 597
Posted By GST
The most reliable mthap prediction is the first...

The most reliable mthap prediction is the first one listed, L3e2a, but it appears the results were incomplete or not read correctly by mthap. Most of the extra mutations listed (73A 750A 4769A 8701A...
Forum: Group Administrators - Advanced Chat 21st January 2018, 11:02 AM
Replies: 5
Views: 611
Posted By GST
Darren - I will send you another message for a...

Darren - I will send you another message for a grandmother, mother and daughter who all tested the full mtDNA sequence and who have multiple problems: incorrect subclade assignment for the...
Forum: Group Administrators - Advanced Chat 18th January 2018, 10:24 PM
Replies: 5
Views: 611
Posted By GST
Hi Darren - I sent you the details in a private...

Hi Darren - I sent you the details in a private message.

Thanks,
Gail
Forum: Group Administrators - Advanced Chat 16th January 2018, 11:53 PM
Replies: 5
Views: 611
Posted By GST
correcting mtDNA subclade assignments

Hi - I have a mtDNA haplogroup project member who was not assigned to the correct subclade because of a common and relatively trivial back mutation. Other project members were assigned to the correct...
Forum: mtDNA - Advanced Topics 7th January 2018, 03:41 PM
Replies: 2
Views: 596
Posted By GST
It depends on what mutations are being counted as...

It depends on what mutations are being counted as steps, and it also depends on how many recent mutations there are in your maternal line. Matches with a genetic distance of 1 or 2 steps could share...
Forum: mtDNA - Advanced Topics 31st December 2017, 10:07 AM
Replies: 1
Views: 490
Posted By GST
There is no way to know without comparing the...

There is no way to know without comparing the detailed full sequence results. Is there an active haplogroup V project? You can also compare results to Ian Logan's GenBank database to see if there...
Forum: mtDNA - Genealogy Basics 31st December 2017, 10:02 AM
Replies: 2
Views: 450
Posted By GST
For the mtDNA test, there is no need to test...

For the mtDNA test, there is no need to test anyone else on the same maternal line because they will all have identical or nearly identical mtDNA results. It is better to use the funds to test more...
Forum: mtDNA - Genealogy Basics 31st December 2017, 09:57 AM
Replies: 7
Views: 785
Posted By GST
For most people the mtDNA full sequence test will...

For most people the mtDNA full sequence test will identify a group of exact and close matches who share a common maternal ancestor typically between 1000 to 4000 years ago, depending on how many...
Forum: mtDNA - Advanced Topics 8th December 2017, 05:28 PM
Replies: 10
Views: 1,702
Posted By GST
It appears that the RSRS is always the reference...

It appears that the RSRS is always the reference used for the genetic distance, not the reference value of the marker for the haplogroup. I listed two examples below for hapgroup H10 for which 16093...
Forum: mtDNA - Advanced Topics 8th December 2017, 11:29 AM
Replies: 10
Views: 1,702
Posted By GST
Yes, in your FTDNA full sequence match list the...

Yes, in your FTDNA full sequence match list the heteroplasmy counts as 1 step in the genetic distance. Heteroplasmies are more common at some markers than others, and I generally ignore common...
Forum: mtDNA - Advanced Topics 8th December 2017, 11:01 AM
Replies: 4
Views: 611
Posted By GST
You can upload your 23andMe mtDNA results to...

You can upload your 23andMe mtDNA results to James Lick's mthap web tool. This will give you a list of the SNPs relative to the rCRS or RSRS reference sequences which you can then compare your FTDNA...
Forum: mtDNA - Genealogy Basics 5th November 2017, 10:36 AM
Replies: 32
Views: 3,716
Posted By GST
Back mutations do occur in mtDNA but they are...

Back mutations do occur in mtDNA but they are relatively infrequent compared to the total set of mutations that define a haplogroup, and when you test the full sequence different subclades will not...
Forum: mtDNA - Genealogy Basics 5th November 2017, 01:33 AM
Replies: 32
Views: 3,716
Posted By GST
Here is another way to look at the results, for...

Here is another way to look at the results, for my subclade U5a2a1 which is estimated to be about 6000 years old, there are 185 full sequence samples in the U5 project and in GenBank. On average...
Forum: mtDNA - Genealogy Basics 5th November 2017, 12:56 AM
Replies: 32
Views: 3,716
Posted By GST
For the mutation rate, the 2009 Soares et al....

For the mutation rate, the 2009 Soares et al. paper "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". Here is the key text: "The substitution rate for the entire...
Forum: mtDNA - Genealogy Basics 4th November 2017, 12:58 PM
Replies: 32
Views: 3,716
Posted By GST
The number of generations in the chart are wrong...

The number of generations in the chart are wrong by about a factor of 10. That is a very poor approximation. But the real problem is that, because of the large variability in the accumulation of new...
Forum: mtDNA - Genealogy Basics 1st November 2017, 10:39 PM
Replies: 32
Views: 3,716
Posted By GST
The genetic distance chart is not accurate - on...

The genetic distance chart is not accurate - on average, the number of generations should be increased by about a factor of 10, but average genetic distances are not very meaningful for evaluating...
Forum: mtDNA - Haplogroup & Origins Basics 1st October 2017, 11:43 AM
Replies: 12
Views: 2,334
Posted By GST
It is also possible that your T1a1 lineage...

It is also possible that your T1a1 lineage originated in the Middle East and was part of the early Jewish Diaspora. The lack of additional recent mtDNA mutations makes it impossible to determine the...
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